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Table 3 Annual prevalence of reactive syphilis results among HIV-positive participants in the OHTN Cohort Study, 2000-09

From: Patterns of syphilis testing in a large cohort of HIV patients in Ontario, Canada, 2000–2009

  N under observation Not tested Non-reactive Reactive Reactive & acute (a)
   N % N % N % N %
MSM          
2000 1139 1108 97.3 19 1.7 6 0.5 1 0.1
2001 1076 1019 94.7 35 3.3 4 0.4 1 0.1
2002 1093 1006 92.0 67 6.1 12 1.1 5 0.5
2003 1050 927 88.3 83 7.9 36 3.4 15 1.4
2004 1114 899 80.7 162 14.5 47 4.2 17 1.5
2005 1101 708 64.3 330 30.0 61 5.5 15 1.4
2006 1066 576 54.0 384 36.0 100 9.4 12 1.1
2007 1071 575 53.7 392 36.6 103 9.6 7 0.7
2008 1893 1007 53.2 631 33.3 246 13.0 47 2.5
2009 2309 988 42.8 918 39.8 400 17.3 88 3.8
P-value for time trend     P < 0.0001 P < 0.0001
Non-MSM Males         
2000 254 247 97.2 5 2.0 1 0.4 0 0
2001 245 226 92.2 14 5.7 2 0.8 0 0
2002 253 239 94.5 11 4.3 3 1.2 1 0.4
2003 246 231 93.9 11 4.5 4 1.6 1 0.4
2004 266 238 89.5 28 10.5 0 0 0 0
2005 262 192 73.3 67 25.6 3 1.1 0 0
2006 255 170 66.7 75 29.4 10 3.9 1 0.4
2007 259 165 63.7 84 32.4 10 3.9 0 0
2008 388 274 70.6 102 26.3 12 3.1 0 0
2009 449 244 54.3 192 42.8 11 2.4 0 0
P-value for time trend     P = 0.0002 P = 0.4443
Females          
2000 197 191 97.0 5 2.5 0 0 0 0
2001 190 177 93.2 10 5.3 0 0 0 0
2002 208 189 90.9 19 9.1 0 0 0 0
2003 201 189 94.0 12 6.0 0 0 0 0
2004 226 200 88.5 26 11.5 0 0 0 0
2005 225 166 73.8 59 26.2 0 0 0 0
2006 233 142 60.9 89 38.2 1 0.4 0 0
2007 238 149 62.6 88 37.0 1 0.4 0 0
2008 425 293 68.9 125 29.4 7 1.6 0 0
2009 499 254 50.9 234 46.9 11 2.2 0 0
P-value for time trend     P < 0.0001 n/a
  1. Percentages shown are row percents. For participants who underwent testing more than once in a single calendar year and had both reactive and non-reactive results, we classified their results as reactive. P-values for calendar year time trends were calculated using logistic regression with GEE.
  2. (a) Acute reactive results were defined as a reactive trepomenal test and RPR titre greater than or equal to 1:16.