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Table 3 Ciprofloxacin dosages in 98 children

From: Current ciprofloxacin usage in children hospitalized in a referral hospital in Paris

    Dose (mg/kg/day) Frequency of administration Adequate dose* n (%)
   n Min Max Median Mean (SD) qd b.i.d t.i.d
Patients without CF oral cipro 32 15 50 20 23(7) 1 30 1 31 (96.9)
i.v. cipro 45 10 60 20 23(9) 1 36 8 38 (84..4)
Total 77 10 60 20 23(8) 2 66 9 69 (89.6)
Patients with CF oral cipro 20 30 50 40 37(5) 0 19 1 13 (61.9)
i.v. cipro 1 / / / / 0 1 0 1 (100)
Total 21 30 50 40 37(5) 0 20 1 14 (66.7)
Total   98 10 60 20 26(9) 2 86 10 83 (84.7)
  1. * Adequate dose in patients without CF was considered as 6 to 10 mg/kg/dose intravenous t.i.d. or 10 to 15 mg/kg/dose orally b.i.d. in children with CF, 10 or 15 mg/kg/dose intravenous three times daily or twice daily followed by 20 mg/kg/dose per os twice daily.