Table 2 Risk factors for ICU admission among 2751 HIV positive patients attending King’s College Hospital, South London, UK
Crude IRR | P-value | Adjusted IRR | P-value | |
|---|---|---|---|---|
Age (per 10 year increase) | 1.39 (1.17, 1.66) | 0.001 | 1.21 (0.95, 1.54) | 0.13 |
Female sex | 1.46 (1.22, 2.20) | 0.03 | 1.11 (0.79, 3.48) | 0.48 |
Black ethnicity | 0.99 (0.65, 1.52) | 0.99 | ||
HIV risk factor | ||||
Heterosexual | 1 | 1 | ||
Homosexual | 0.57 (0.33, 0.98) | 0.04 | 0.64 (0.33, 1.25) | 0.19 |
IVDU | 1.79 (0.81, 3.95) | 0.15 | 1.01 (0.34, 2.96) | 0.99 |
Hepatitis B surface antigen positive | 1.95 (0.99, 3.82) | 0.07 | 1.46 (0.65, 3.28) | 0.36 |
Hepatitis C antibody positive | 0.63 (0.23, 1.73) | 0.94 | ||
AIDS (CDC-C) | 9.58 (5.42, 16.9) | <0.0001 | 6.94 (3.73, 12.9) | <0.0001 |
CD4 cell count (cells/mm3) | ||||
>350 | 1 | 1 | ||
200-350 | 1.01 (0.48, 2.02) | 1.00 | 0.98 (0.45, 2.15) | 0.97 |
100-200 | 2.89 (1.39, 5.85) | 0.003 | 2.22 (1.01, 4.88) | 0.05 |
50-100 | 12.5 (6.35, 24.6) | <0.0001 | 2.70 (0.92, 7.98) | 0.07 |
<50 | 21.0 (11.7, 37.8) | <0.0001 | 6.11 (2.99, 12.5) | <0.0001 |
Initiated cART | 0.17 (0.11, 0.27) | <0.0001 | 0.11 (0.07, 0.19) | <0.0001 |
HIV RNA <400 copies/mL | 0.73 (0.44, 1.24) | 0.31 |