Table 2 Function predictions of essential genes for reference strains H37Rv, H37Ra, CDC1511, F11, KZN1435

Replication

10

10

10

10

10

(0.01%)

(0.01%)

(0.02%)

(0.01%)

(0.01%)

Regulatory proteins

10

10

10

10

10

(0.01%)

(0.01%)

(0.02%)

(0.01%)

(0.01%)

Virulence

288

293

284

292

291

(42.10%)

(41.74%)

(42.71%)

(41.77%)

(41.75%)

Intermediary metabolism and respiration

265

270

260

269

266

(38.74%)

(38.46%)

(39.10%)

(38.48%)

(38.16%)

Cell wall related

297

302

295

302

299

(43.42%)

(43.021%)

(44.36%)

(43.20%)

(42.90%)

information pathway

251

255

248

256

253

(36.70%)

(36.32%)

(37.29%)

(36.62%)

(36.30%)

Lipid metabolism

257

263

254

263

260

(37.57%)

(37.46%)

(38.20%)

(37.63%)

(37.30%)

PE/PPE family

11

14

8

14

13

(0.02%)

(0.02%)

(0.01%)

(0.02%)

(0.02%)

Insertion seqs and phages

12

13

10

13

12

(0.02%)

(0.02%)

(0.02%)

(0.02%)

(0.02%)

Hypothetical/unknown

261

269

255

269

268

(38.15%)

(38.31%)

(38.35%)

(38.48%)

(38.45%)