Table 3 Association between maternal cytokine gene polymorphisms and mothers’ biological parameters: multivariate analysis
Maternal cytokine gene (n) | Haemoglobin (g/dl) (SD)a | P b | Anaemia OR [CI95]c | P b | P. falciparumplacenta infection OR [CI95]d | P e |
|---|---|---|---|---|---|---|
IL-4 −590 genotypes: |  |  |  |  |  |  |
 CC (25) | 11.2 (0.3) |  | 1 |  |  |  |
 CT (193) | 11.1 (0.3) | 0.88 | 1.13 [0.48-2.65] | 0.77 |  |  |
 TT (358) | 11.3 (0.3) | 0.65 | 0.87 [0.38-1.98] | 0.73 | OR CT and TT vs. CC = 0.36 [0.14-0.93] | 0.03 |
IL-4 +33 genotypes: | Â | Â | Â | Â | Â | Â |
 CC (145) | 11.3 (0.2) |  |  |  |  |  |
 CT and TT (431) | 11.6 (0.1) | 0.03 | OR CT and TT vs. CC = 0.66 [0.44-0.97] | 0.04 | OR CT and TT vs. CC = 0.54 [0.31-0.94] | 0.03 |
IL-4 −590 /IL-4 +33 haplotypes: |  |  |  |  |  |  |
 No IL4-TT (145) | 11.3 (0.2) |  |  |  |  |  |
 1 or 2 copies IL4-TT (431) | 11.6 (0.1) | 0.03 | OR 1 or 2 copies IL4-TT vs. no IL4-TT = 0.66 [0.44-0.97] | 0.04 | OR 1 or 2 copies IL4-TT vs. no IL4-TT = 0.54 [0.31-0.94] | 0.03 |
IL-10 −1082 genotypes: |  |  |  |  |  |  |
 GG (47) | 11.4 (0.2) |  | 1 |  |  |  |
 GA (223) | 11.3 (0.2) | 0.53 | 1.01 [0.52-1.94] | 0.98 |  |  |
 AA (306) | 11.3 (0.2) | 0.59 | 1.23 [0.65-2.34] | 0.52 | OR AA vs GG and GA = 1.95 [1.11-3.42] | 0.02 |