Table 2 Distribution of cytokine gene polymorphisms in the study population of 576 mothers
Gene | SNPs | Location in the gene | Genotype | Frequency in the study population | Hardy-Weinberg equilibrium test χ2(P-value, df = 2) |
|---|---|---|---|---|---|
IL-4 | rs2243250 | −590 C/T | CC | 25 (4%) | χ 2 = 0.03 (P = 0.98) |
| Â | Â | Â | CT | 193 (34%) | Â |
| Â | Â | Â | TT | 358 (62%) | Â |
|  | rs2070874 | +33 C/T | CC | 145 (25%) | χ 2 = 0.08 (P = 0.96) |
| Â | Â | Â | CT | 290 (50%) | Â |
| Â | Â | Â | TT | 141 (25%) | Â |
IL-10 | rs1800896 | −1082 G/A | GG | 47 (8%) | χ 2 = 0.63 (P = 0.73) |
| Â | Â | Â | GA | 223 (39%) | Â |
| Â | Â | Â | AA | 306 (53%) | Â |
|  | rs1800871 a | −819 C/T | CC | 184 (33%) | χ 2 = 1.09 (P = 0.58) |
| Â | Â | Â | CT | 281 (51%) | Â |
| Â | Â | Â | TT | 90 (16%) | Â |
|  | rs1800872 | −592 C/A | CC | 191 (33%) | χ 2 = 1.64 (P = 0.44) |
| Â | Â | Â | CA | 294 (51%) | Â |
| Â | Â | Â | AA | 91 (16%) | Â |
IL-13 | rs1800925 | −1055 C/T | CC | 186 (32%) | χ 2 = 1.48 (P = 0.48) |
| Â | Â | Â | CT | 295 (51%) | Â |
| Â | Â | Â | TT | 95 (17%) | Â |