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Table 1 Comparison of 110 patients with asymptomatic bacteriuria to 177 patients with symptomatic urinary tract infection due to E. coli

From: Patient characteristics but not virulence factors discriminate between asymptomatic and symptomatic E. coli bacteriuria in the hospital

Variable Asymptomatic bacteriuria (n = 110) Symptomatic urinary tract infection (n = 177) p value Adjusted odds ratio (95% CI)*
  n (%) n (%)   
Gender (male) 19 (17) 43 (24) 0.2  
Age (years, median, range) 67 (20, 100) 64 (19, 101) 0.1  
Race (white) 68 (62) 101 (57) 0.4  
Body mass index (kg/m2, mean, ±SD) 28.9 (±8.4) 28.9 (±9.9) 1.0  
Diabetes mellitus 39 (36) 53 (30) 0.3  
Renal insufficiency (Cr > 1.5 mg/dl) 23 (21) 37 (21) 1.0  
Any malignancy 28 (26) 44 (25) 0.9  
Any transplant 3 (3) 9 (5) 0.3  
Neutropenia at time of bacteriuria (ANC <1000/ul) 0 7 (4) 0.046  
Pregnancy 5 (5) 8 (6) 1.0  
Congestive heart failure 26 (24) 24 (14) 0.03  
Myocardial infarction 23 (21) 18 (10) 0.01  
Chronic pulmonary disease 25 (23) 24 (14) 0.045 2.1 (1.04-4.1)
Peripheral vascular disease 9 (8) 5 (3) 0.04  
Oral steroid medication 6 (5) 15 (8) 0.3  
Dementia 15 (14) 11 (6) 0.03 2.4 (1.02-5.8)
History of cerebrovascular accident 24 (22) 36 (20) 0.8  
Hemi- or paraplegia 13 (12) 14 (8) 0.3  
Functional or anatomical urinary tract abnormalities 31 (28) 54 (31) 0.7  
Voiding dysfunction 26 (24%) 54 (31%) 0.2  
Benign prostatic hyperplasia (n = 62) 3/19 (16) 15/43 (35) 0.1  
History of urogenital surgery 30 (27) 61 (34) 0.8  
Urological procedure this admission 0 5 (3) 0.2  
Charlson comorbidity index (mean, ±SD) 3.1 (±2.6) 2.8 (±2.8) 0.2  
McCabe severity-of-illness score (median, range) 1 (1, 2) 1 (1, 3) 0.2  
Cystitis - 70 (39) -  
Pyelonephritis - 107 (62) -  
Sepsis 38 (35) 108 (61) <0.001  
Sepsis-induced hypotension 7 (6) 41 (23) <0.001  
Community-acquired bacteriuria 75 (68) 127 (72) 0.5  
Urinary catheter-associated bacteriuria 22 (20) 30 (17) 0.5  
Urinalysis with pyuria (>10 WBC/hpf) 65 (63) 121 (74) 0.1  
Isolate resistant to ciprofloxacin 57 (32%) 41 (37%) 0.4  
Isolate resistant to trimethoprim/ sulfamethoxazole 45 (25%) 32 (29%) 0.5  
Outcomes     
Pathogen-directed antibiotic treatment 89 (81) 168 (95) <0.001  
Length of hospital stay (mean, ±SD) 5.5 (±7.7) 6.6 (±7.5) 0.2  
In-hospital mortality 4 (3.6) 8 (5) 0.5  
  1. NOTE. CI = confidence interval. SD = standard deviation. Cr = creatinine. ANC = absolute neutrophil count. WBC = white blood cells. HPF = high-power field.
  2. * The variables included in the final model were neutropenia, congestive heart failure, chronic pulmonary disease, history of myocardial infarction, peripheral vascular disease, dementia, and pyuria.