Skip to main content

Table 1 Predicted CD4+ HA T cell epitopes of A(H1N1)pdm09 viruses and their conservancy in seasonal H1N1 (1977–2009) viruses

From: T cell memory to evolutionarily conserved and shared hemagglutinin epitopes of H1N1 viruses: a pilot scale study

Predicted CD4+ T- cell epitopes (15 a. a) (epitope position) % of predicted epitope conservancy in seasonal H1N1(1977–2009) HA proteins % seasonal H1N1(1977–2009) isolates with each of the conserved epitope % A(H1N1)pdm09 (2009–2010) isolates with each of the conserved epitope
VLEKNVTVTHSVNLL 100 100 99
(HA1 19–33)    
EELREQLSSVSSFER 100 100 99
(HA1 99–113)    
QLSSVSSFERFEIFP 100 100 99
(104–119)    
ATGLRNIPSIQSRGL 93 97 98
(HA1 315–329)    
GLRNIPSIQSRGLFG 100 97 100
(HA1 317–331)    
RNIPSIQSRGLFGAI 100 97 98
(HA1 319–333)    
QSRGLFGAIAGFIEG 100 100 100
(HA1 325339)    
NKVNSVIEKMNTQFT 100 96 99
(HA2 377–391)    
VIEKMNTQFTAVGKE 100 96 99
(HA2 382–396)    
DGFLDIWTYNAELLV 100 96 99
(HA2 413–427)    
WTYNAELLVLLENER 100 99 100
(HA2 419–433)    
TYNAELLVLLENERT 100 99 100
(HA2 420–434)    
YNAELLVLLENERTL 100 100 100
(HA2 421–435)    
LVLLENERTLDYHDS 100 98 100
(HA2 426–440)    
I YQILAIYSTVASSL 93 100 100
(HA2 510–524)    
YQILAIYSTVASSLV 100 100 100
(HA2 511–525)    
STVASSLVL L VSLGA 93 100 98
(HA2 518–532)    
GAISFWMCSNGSLQC 100 98 99
(HA2 531–545)    
  1. Bold faced epitopes were used in in vitro assays.