Table 1 Demographic, immunological and virological profile of the vertically-HIV infected patients in the CoRISpe
Group A <18 years | Group B ≥18 years | Total | |
|---|---|---|---|
N=520 | N=282 | N=802 | |
Age (years) mean (range) | 12,6 (0,04-17,98) | 22 (18,1-29,7) | 15,1 (0,04-29,7) |
Sex: N (%) | |||
Male | 241 (46,3) | 127 (45) | 368 (45,9) |
Female | 279 (53,7) | 155 (55) | 434 (54,1) |
Origin: N (%) | |||
Spain | 353 (67,9) | 261 (92,5) | 614 (76,6) |
Sub-Saharan Africa | 102 (19,6) | 7 (2,5) | 109 (13,6) |
Latin America | 39 (7,5) | 7 (2,5) | 46 (5,7) |
North Africa | 10 (1,9) | 3 (1,1) | 13 (1,6) |
East Europe | 9 (1,7) | 0 (0,0) | 9 (1,1) |
Asia | 4 (0,8) | 1 (0,3) | 5 (0,6) |
West Europe | 3 (0,6) | 3 (1,1) | 6 (08) |
Time of identification of infection | |||
At Birth | 79 (15,2) | 11 (3,9) | 90 (11,2) |
After Birth (asymptomatic) | 264 (50,8) | 160 (56,7) | 424 (52,9) |
After Birth (symptomatic) | 151 (29) | 87 (30,9) | 238 (29,7) |
Unknown | 26 (5) | 24 (8,5) | 50 (6,2) |
Group age at 1st presentation (years) | |||
<1 | 316 (60,8) | 104 (36,9) | 420 (52,3) |
1-5 | 150 (28,8) | 132 (46,8) | 282 (35,2) |
≥6 | 54 (10,4) | 46 (16,3) | 100 (12,5) |
Group year of 1st presentation (years) | |||
1975-1990 | 0 (0,0) | 73 (25,9) | 73 (9,1) |
1991-2000 | 289 (55,6) | 199 (70,6) | 488 (60,8) |
2001-2011 | 231 (44,4) | 10 (3,5) | 241 (30,1) |
Group age at most recent follow-up visit (years) | |||
0-5 | 70 (13,5) | 0 (0,0) | 70 (8,7) |
6-11 | 209 (40,2) | 0 (0,0) | 209 (26,1) |
12-17 | 241 (46,3) | 0 (0,0) | 241 (30) |
≥18 | 0 (0,0) | 282 (100) | 282 (35,2) |
CDC: N (%) | |||
N-A | 270 (51,9) | 91 (32,3) | 361 (45) |
B | 127 (24,4) | 106 (37,6) | 233 (29,1) |
C | 123 (23,7) | 85 (30,1) | 208 (25,9) |
Co-infections: N (%) | |||
HCV | 24 (4,6) | 31 (11) | 55 (6,9) |
HBV | 7 (1,3) | 3 (1,1) | 10 (1,3) |
CMV | 19 (3,7) | 3 (1,1) | 22 (2,7) |
Other | 4 (0,8) | 2 (0,7) | 6 (0,7) |
No Co-infections | 466 (89,6) | 243 (86,1) | 709 (88,4) |
Immunological status (%CD4) N (%) | |||
<15% | 9 (1,8) | 20 (7,1) | 29 (3,6) |
15-25% | 49 (9,4) | 49 (17,4) | 98 (12,3) |
>25% | 462 (88,8) | 183 (64,9) | 645 (80,4) |
Unknown | 0 (0,0) | 30 (10,6) | 30 (3,7) |
Viral load (copies/ml) N (%) | |||
<50 | 341 (65,6) | 134 (47,5) | 475 (59,2) |
50-10000 | 92 (17,7) | 83 (29,4) | 175 (21,8) |
>10000 | 27 (5,2) | 36 (12,8) | 63 (7,9) |
Unknown | 60 (11,5) | 29 (10,3) | 89 (11,1) |