Allele | ACL | Controls (n = 260) | P-value | Pc-value | OR | 95%CI | ||
---|---|---|---|---|---|---|---|---|
n | F% | n | F % | |||||
ACL overall (n = 169) | ||||||||
HLA-B*45 | 0 | - | 12 | 2.3 | 0.0046 | 0.1426 | - | - |
HLA-DRB1*13 | 51 | 15.1 | 54 | 10.4 | 0.0431 | 0.6465 | 1.53 | 1.01-2.31 |
ACL (group 1; n = 136) | ||||||||
HLA-DRB1*13 | 44 | 16.2 | 54 | 10.4 | 0.0228 | 0.3420 | 1.66 | 1.08-2.55 |
HLA-B*35 | 53 | 19.5 | 68 | 13.1 | 0.0218 | 0.6758 | 1.67 | 1.08-2.29 |
HLA-B*44 | 38 | 14.0 | 46 | 8.9 | 0.0290 | 0.8990 | 1.67 | 1.05-2.64 |
HLA-B*45 | 0 | - | 12 | 2.3 | 0.0107 | 0.3317 | - | - |
ACL (group 1A; n = 118) | ||||||||
HLA-B*44 | 35 | 14.8 | 46 | 8.9 | 0.0160 | 0.4969 | 1.79 | 1.12-2.87 |
HLA-B*45 | 0 | - | 12 | 2.3 | 0.0231 | 0.0225 | - | - |
HLA-DRB1*13 | 38 | 16.1 | 54 | 10.4 | 0.0152 | 0.2280 | 1.65 | 1.06-2.59 |
ACL (group 2; n = 15) | ||||||||
HLA-B*27 | 3 | 10.0 | 8 | 1.5 | 0.0180 | 0.5580 | 7.11 | 1.78-28.33 |
ACL (group 3B; n = 7) | ||||||||
HLA-B*52 | 3 | 21.4 | 11 | 2.1 | 0.0044 | 0.1360 | 12.61 | 3.08-51.66 |
ACL (group 4; n = 22) | ||||||||
HLA-B*49 | 4 | 9.1 | 8 | 1.5 | 0.0101 | 0.3131 | 6.4 | 1.8-22.17 |