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Table 1 Frequency of HLA-A, -B and -DRB1 alleles in the ACL group versus the control group

From: Association between HLA genes and American cutaneous leishmaniasis in endemic regions of Southern Brazil

  ACL (n = 169) Controls (n = 260)       ACL (n = 169) Controls (n = 260)     
Allele n F % n F % P -value Pc-value OR 95%CI Allele n F% n F% P -value Pc-value OR 95%CI
HLA – A*          HLA-B*         
01 37 10.9 47 9.0 ns -    07 20 5.9 38 7.3 ns -   
02 95 28.1 127 24.4 ns -    08 16 4.7 34 6.5 ns -   
03 30 8.8 56 10.8 ns -    13 1 0.3 9 1.7 ns -   
11 23 6.8 26 5.0 ns -    14 15 4.4 22 4.2 ns -   
23 18 5.3 22 4.2 ns -    15 26 7.7 48 9.2 ns -   
24 37 10.9 62 11.9 ns -    18 17 5.0 36 6.9 ns -   
25 4 1.2 13 2.5 ns -    27 7 2.1 8 1.5 ns -   
26 11 3.2 18 3.5 ns -    35 58 17.2 68 13.1 ns -   
29 9 2.6 28 5.4 ns -    37 1 0.3 5 1.0 ns -   
30 11 3.2 25 4.8 ns -    38 10 3.0 15 2.9 ns -   
31 18 5.3 19 3.7 ns -    39 13 3.9 18 3.5 ns -   
32 8 2.3 16 3.1 ns -    40 18 5.3 16 3.1 ns -   
33 5 1.5 15 2.9 ns -    41 2 0.6 6 1.2 ns -   
34 3 0.9 5 1.0 ns -    42 2 0.6 6 1.2 ns -   
36 2 0.6 2 0.4 ns -    44 43 12.7 46 8.9 ns -   
39 1 0.3 - - ns -    45 0 - 12 2.3 0.0046 0.1426 - -
66 3 0.9 1 0.2 ns -    46 0 - 4 0.8 ns -   
68 19 5.62 35 6.7 ns -    47 0 - 1 0.2 ns -   
74 4 1.9 3 0.6 ns -    48 3 0.9 2 0.4 ns -   
HLA-DRB1*          49 8 2.4 8 1.5 ns -   
01 23 6.8 42 8.1 ns -    50 8 2.4 14 2.7 ns -   
03 32 9.5 61 11.7 ns -    51 29 8.6 44 8.5 ns -   
04 40 11.8 56 10.8 ns -    52 10 3.0 11 2.1 ns -   
07 39 11.5 67 12.9 ns -    53 7 2.1 8 1.5 ns -   
08 26 7.7 30 5.8 ns -    54 1 0.3 3 0.6 ns -   
09 4 1.2 4 0.8 ns -    55 8 2.4 12 2.3 ns -   
10 5 1.5 10 1.9 ns -    56 2 0.6 1 0.2 ns -   
11 45 13.3 81 15.6 ns -    57 7 2.1 12 2.3 ns -   
12 3 0.9 10 1.9 ns -    58 6 1.8 10 1.9 ns -   
13 51 15.1 54 10.4 0.0431 0.6465 1.53 1.01-2.31 73 0 - 1 0.2 ns -   
14 19 5.6 40 7.7 ns -    81 0 - 2 3.9 ns -   
15 34 10.1 44 8.8 ns -            
16 17 5.0 21 4.0 ns -            
  1. n = number of times the allele occurs; F = allele frequency; P-value = calculated by Fisher’s exact test; Pc-value = value of p corrected by Bonferroni correction; OR = odds ratio; 95%CI = 95% confidence interval; ns= not significant (p > 0.05).