Prognostic factor
|
No infiltrate and no bacteraemia patients
|
Infiltrate without bacteraemia patients
|
Bacteraemia patients
|
---|
|
n (%)
|
Crude MRR (95 % CI) a
|
Adjusted MRR (95% CI) a,b
|
n (%)
|
Crude MRR (95% CI) a
|
Adjusted MRR (95% CI) a,b
|
n (%)
|
Crude MRR (95 % CI) a
|
Adjusted MRR (95% CI) a,b
|
---|
All patients
|
9 (5)
|
1.0 (ref.)
|
1.0 (ref.)
|
27 (11)
|
2.4 (1.1-5.0)
|
1.9 (0.9-4.1)
|
54 (21)
|
4.8 (2.4-9.6)
|
4.1 (2.0-8.5)
|
Age group (years)
|
|
15-49
|
0 (0)
|
1.0 (ref.)
|
1.0 (ref.)
|
3 (8)
|
NA
|
NA
|
2 (4)
|
NA
|
NA
|
|
50-74
|
5 (4)
|
1.0 (ref.)
|
1.0 (ref.)
|
13 (10)
|
2.3 (0.8-6.6)
|
2.1 (0.7-6.0)
|
28 (22)
|
5.5 (2.1-14.3)
|
5.2 (2.0-13.8)
|
|
≥75
|
4 (7)
|
1.0 (ref.)
|
1.0 (ref.)
|
11 (13)
|
1.8 (0.6-5.8)
|
1.6 (0.5-5.3)
|
24 (28)
|
4.1 (1.4-11.9)
|
3.3 (1.1-9.9)
|
Sex
| | | | | | | | | | |
|
Women
|
3 (4)
|
1.0 (ref.)
|
1.0 (ref.)
|
7 (8)
|
2.2 (0.6-8.3)
|
2.2 (0.6-9.0)
|
20 (16)
|
4.7 (1.4-15.9)
|
4.3 (1.2-15.6)
|
|
Men
|
6 (5)
|
1.0 (ref.)
|
1.0 (ref.)
|
20 (13)
|
2.3 (0.9-5.8)
|
1.8 (0.7-4.5)
|
34 (24)
|
4.9 (2.1-11.7)
|
4.2 (1.7-10.3)
|
Comorbidity index
|
|
Index low (0)
|
1 (3)
|
1.0 (ref.)
|
1.0 (ref.)
|
4 (6)
|
2.1 (0.2-18.6)
|
1.5 (0.2-14.7)
|
15 (15)
|
5.7 (0.7-42.8)
|
4.1 (0.5-32.5)
|
|
Index medium (1–2)
|
2 (2)
|
1.0 (ref.)
|
1.0 (ref.)
|
13 (14)
|
7.1 (1.6-31.5)
|
5.8 (1.3-26.2)
|
14 (17)
|
8.9 (2.0-39.1)
|
8.1 (1.8-36.8)
|
|
Index high (≥3)
|
5 (9)
|
1.0 (ref.)
|
1.0 (ref.)
|
10 (12)
|
1.1 (0.4-3.1)
|
0.8 (0.3-2.3)
|
25 (31)
|
3.5 (1.4-8.5)
|
2.9 (1.2-7.3)
|
Chronic pulmonary disease c
|
|
Yes
|
6 (5)
|
1.0 (ref.)
|
1.0 (ref.)
|
12 (11)
|
2.0 (0.7-5.3)
|
1.3 (0.5-3.5)
|
14 (24)
|
4.8 (1.9-12.6)
|
3.8 (1.4-10.3)
|
|
No
|
3 (4)
|
1.0 (ref.)
|
1.0 (ref.)
|
15 (11)
|
3.1 (0.9-10.5)
|
2.6 (0.7-9.4)
|
40 (20)
|
5.7 (1.8-18.6)
|
4.5 (1.4-14.9)
|
CRP (mg/L)
|
|
<100
|
1 (1)
|
1.0 (ref.)
|
1.0 (ref.)
|
8 (10)
|
10.7 (1.3-85.8)
|
11.3 (1.4-95.4)
|
7 (32)
|
35.6 (4.4-290)
|
27.6 (2.8-267)
|
|
100-199
|
3 (6)
|
1.0 (ref.)
|
1.0 (ref.)
|
6 (9)
|
1.5 (0.4-6.1)
|
1.1 (0.2-5.3)
|
4 (13)
|
2.2 (0.5-9.6)
|
2.8 (0.5-15.7)
|
|
≥200
|
4 (17)
|
1.0 (ref.)
|
1.0 (ref.)
|
12 (13)
|
0.8 (0.3-2.4)
|
0.6 (0.2-2.1)
|
41 (21)
|
1.3 (0.5-3.6)
|
1.3 (0.5-3.6)
|
Leukocyte count (109/L)
|
|
<3,5
|
1 (100)
|
1.0 (ref.)
|
1.0 (ref.)
|
3 (38)
|
0.1 (0.0-2.1)
|
NA
|
8 (47)
|
0.3 (0.0-2.3)
|
0.2 (0.0-3.4)
|
|
3.5-8.7
|
0 (0)
|
1.0 (ref.)
|
1.0 (ref.)
|
1 (4)
|
NA
|
NA
|
7 (32)
|
NA
|
NA
|
|
8.8-14.9
|
3 (3)
|
1.0 (ref.)
|
1.0 (ref.)
|
12 (12)
|
3.7 (1.1-13.3)
|
2.8 (0.7-10.4)
|
8 (14)
|
4.4 (1.2-16.4)
|
2.7 (0.7-11.6)
|
|
≥15.0
|
4 (6)
|
1.0 (ref.)
|
1.0 (ref.)
|
10 (10)
|
1.7 (0.5-5.4)
|
1.3 (0.4-4.4)
|
29 (19)
|
3.5 (1.2-10.0)
|
3.2 (1.1-9.5)
|
- LRTI, lower respiratory tract infection; MRR, mortality rate ratio; CI, confidence interval; ref, reference; NA, not applicable because of too few events to calculate MRRs; CRP, C-reactive protein.
-
a MRR estimates are calculated using cox-regression.
-
b MRR estimates are adjusted for age, sex, comorbidity, smoking, and alcohol intake (except when stratified by variable).
-
c Chronic pulmonary disease: ICD-8: 490–493, 515–518. ICD-10: DJ40-DJ47, DJ60-DJ67, DJ68.4, DJ70.1, DJ70.3, DJ84.1, DJ92.0, DJ96.1, DJ98.2, DJ98.3.