Skip to main content

Table 3 30-day-mortality according to LRTI manifestation group overall and stratified by subgroups

From: Impact of positive chest X-ray findings and blood cultures on adverse outcomes following hospitalized pneumococcal lower respiratory tract infection: a population-based cohort study

Prognostic factor

No infiltrate and no bacteraemia patients

Infiltrate without bacteraemia patients

Bacteraemia patients

 

n (%)

Crude MRR (95 % CI) a

Adjusted MRR (95% CI) a,b

n (%)

Crude MRR (95% CI) a

Adjusted MRR (95% CI) a,b

n (%)

Crude MRR (95 % CI) a

Adjusted MRR (95% CI) a,b

All patients

9 (5)

1.0 (ref.)

1.0 (ref.)

27 (11)

2.4 (1.1-5.0)

1.9 (0.9-4.1)

54 (21)

4.8 (2.4-9.6)

4.1 (2.0-8.5)

Age group (years)

 

15-49

0 (0)

1.0 (ref.)

1.0 (ref.)

3 (8)

NA

NA

2 (4)

NA

NA

 

50-74

5 (4)

1.0 (ref.)

1.0 (ref.)

13 (10)

2.3 (0.8-6.6)

2.1 (0.7-6.0)

28 (22)

5.5 (2.1-14.3)

5.2 (2.0-13.8)

 

≥75

4 (7)

1.0 (ref.)

1.0 (ref.)

11 (13)

1.8 (0.6-5.8)

1.6 (0.5-5.3)

24 (28)

4.1 (1.4-11.9)

3.3 (1.1-9.9)

Sex

          
 

Women

3 (4)

1.0 (ref.)

1.0 (ref.)

7 (8)

2.2 (0.6-8.3)

2.2 (0.6-9.0)

20 (16)

4.7 (1.4-15.9)

4.3 (1.2-15.6)

 

Men

6 (5)

1.0 (ref.)

1.0 (ref.)

20 (13)

2.3 (0.9-5.8)

1.8 (0.7-4.5)

34 (24)

4.9 (2.1-11.7)

4.2 (1.7-10.3)

Comorbidity index

 

Index low (0)

1 (3)

1.0 (ref.)

1.0 (ref.)

4 (6)

2.1 (0.2-18.6)

1.5 (0.2-14.7)

15 (15)

5.7 (0.7-42.8)

4.1 (0.5-32.5)

 

Index medium (1–2)

2 (2)

1.0 (ref.)

1.0 (ref.)

13 (14)

7.1 (1.6-31.5)

5.8 (1.3-26.2)

14 (17)

8.9 (2.0-39.1)

8.1 (1.8-36.8)

 

Index high (≥3)

5 (9)

1.0 (ref.)

1.0 (ref.)

10 (12)

1.1 (0.4-3.1)

0.8 (0.3-2.3)

25 (31)

3.5 (1.4-8.5)

2.9 (1.2-7.3)

Chronic pulmonary disease c

 

Yes

6 (5)

1.0 (ref.)

1.0 (ref.)

12 (11)

2.0 (0.7-5.3)

1.3 (0.5-3.5)

14 (24)

4.8 (1.9-12.6)

3.8 (1.4-10.3)

 

No

3 (4)

1.0 (ref.)

1.0 (ref.)

15 (11)

3.1 (0.9-10.5)

2.6 (0.7-9.4)

40 (20)

5.7 (1.8-18.6)

4.5 (1.4-14.9)

CRP (mg/L)

 

<100

1 (1)

1.0 (ref.)

1.0 (ref.)

8 (10)

10.7 (1.3-85.8)

11.3 (1.4-95.4)

7 (32)

35.6 (4.4-290)

27.6 (2.8-267)

 

100-199

3 (6)

1.0 (ref.)

1.0 (ref.)

6 (9)

1.5 (0.4-6.1)

1.1 (0.2-5.3)

4 (13)

2.2 (0.5-9.6)

2.8 (0.5-15.7)

 

≥200

4 (17)

1.0 (ref.)

1.0 (ref.)

12 (13)

0.8 (0.3-2.4)

0.6 (0.2-2.1)

41 (21)

1.3 (0.5-3.6)

1.3 (0.5-3.6)

Leukocyte count (109/L)

 

<3,5

1 (100)

1.0 (ref.)

1.0 (ref.)

3 (38)

0.1 (0.0-2.1)

NA

8 (47)

0.3 (0.0-2.3)

0.2 (0.0-3.4)

 

3.5-8.7

0 (0)

1.0 (ref.)

1.0 (ref.)

1 (4)

NA

NA

7 (32)

NA

NA

 

8.8-14.9

3 (3)

1.0 (ref.)

1.0 (ref.)

12 (12)

3.7 (1.1-13.3)

2.8 (0.7-10.4)

8 (14)

4.4 (1.2-16.4)

2.7 (0.7-11.6)

 

≥15.0

4 (6)

1.0 (ref.)

1.0 (ref.)

10 (10)

1.7 (0.5-5.4)

1.3 (0.4-4.4)

29 (19)

3.5 (1.2-10.0)

3.2 (1.1-9.5)

  1. LRTI, lower respiratory tract infection; MRR, mortality rate ratio; CI, confidence interval; ref, reference; NA, not applicable because of too few events to calculate MRRs; CRP, C-reactive protein.
  2. a MRR estimates are calculated using cox-regression.
  3. b MRR estimates are adjusted for age, sex, comorbidity, smoking, and alcohol intake (except when stratified by variable).
  4. c Chronic pulmonary disease: ICD-8: 490–493, 515–518. ICD-10: DJ40-DJ47, DJ60-DJ67, DJ68.4, DJ70.1, DJ70.3, DJ84.1, DJ92.0, DJ96.1, DJ98.2, DJ98.3.
Back to article page

BMC Infectious Diseases

ISSN: 1471-2334

Contact us