Table 4 Significant prognostic factors derived from univariate analysis
Survivors | Non survivors | ||
|---|---|---|---|
n = 201 | n = 116 | p | |
Patient characteristics | |||
Age, yrs | 62.9 ± 15.3 | 68.5 ±14.4 | 0.001 |
ICU admission | |||
SAPS II | 40.8 ± 12.0 | 61.3 ± 19.9 | < 0.001 |
SOFA score | 5.7 ± 5.3 | 8.6 ± 3.5 | < 0.001 |
PSI class V, n (%) | 108 (53.7) | 103 (88.8) | < 0.001 |
Leukopenia, n (%) | 10 (5) | 20 (17.2) | < 0.001 |
MV within 48 hrs of admission, n (%) | 124 (61.7) | 109 (94) | < 0.001 |
PaO2:FIO2 < 200 in patients with MV, n (%) | 76 (37.8) | 93 (80.2) | < 0.001 |
Therapeutics interventions | |||
Vasoactive drugs within 48 hrs of admission, n (%) | 88 (43.8) | 95 (81.9) | < 0.001 |
Dobutamine, n (%) | 26 (12.9) | 37 (31.9) | < 0.001 |
Dopamine, n (%) | 7 (3.5) | 11 (9.5) | 0.02 |
Norepinephrine, n (%) | 66 (32.8) | 54 (46.5) | 0.01 |
Epinephrine, n (%) | 7 (3.5) | 24 (20.7) | < 0.001 |
Combination of a 3rdGC and levofloxacin, n (%) | 84 (41.8) | 31 (26.7) | 0.007 |
Mean tidal volume, mLl/kg | 7.14 ± 1 | 7.56 ± 1.41 | 0.008 |
Low-dose steroid administration, n (%) | 47 (23.3) | 42 (36.2) | 0.01 |
Transfusion, n (%) | 48 (23.9) | 54 (46.5) | < 0.001 |
Systematicpost extubation NIMV, n (%) | 21 (10.4) | 7 (6) | 0.01 |
Intervention period, n (%) | 121 (69.1) | 54 (30.8) | 0.01 |