Limits of patient isolation measures to control extended-spectrum beta-lactamase–producing Enterobacteriaceae: model-based analysis of clinical data in a pediatric ward

Table 2 Epidemiological data for both intervention periods

Data	P₁	P₂
Screening policy	all patients, at admission and every Monday	all patients, at admission and every Monday
Isolation policy	within 24 h following test positivity	preemptive isolation of colonized inpatients, otherwise within 24 h following positivity
Type of isolation	single room	8-bed ward
Overflow policy	—	admissions stopped
Admissions, no.	690	333
Days (pt-d)	260 (4165)	148 (2305)
Mean occupancy (range)	16 (6–22)	16 (9–20)
Mean staff-to-patient ratio (range)	0.89 (0.45–2.2)	0.85 (0.5–1.5)
Mean length of stay (range), days	6 (0–83)	6.7 (0–71)
Acquisitions, no.	29	10
K. pneumoniae	20	7
E. coli	4	0
Other species	5	3
Incidence, per 1 000 pt-d	7.0	4.3
K. pneumoniae	4.8	3.0
E. coli	1.0	0.0
Other species	1.2	1.3
Prevalence, %	26	21
K. pneumoniae	18	15
E. coli	3	2
Other species	5	4

The prevalence was computed as the ratio of the total number of colonized patient-days to the total number of patient-days for each period. The incidence was computed as the ratio of the number of acquisitions to the total number of patient-days for each period. The staff-to-patient ratio was computed as the daily ratio of the number of staff members (nurses and ward assistants) to the number of patients. pt-d: patient-days.

ISSN: 1471-2334