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Table 1 Model parameters for both intervention periods

From: Limits of patient isolation measures to control extended-spectrum beta-lactamase–producing Enterobacteriaceae: model-based analysis of clinical data in a pediatric ward

Parameter

Symbol

P1

P2

Sporadic acquisition rate

β 0

0.009 (0.002–0.022)

0.008 (0.001–0.015)

Transmission rate from unisolated patients

β 1

0.006 (0–0.017)

0.006 (0–0.016)

Transmission rate from isolated patients

β 2

0.001 (0–0.005)

0

Admission prevalence

σ

0.18 (0.14–0.22)

0.15 (0.11–0.21)

Isolation rate for imported and acquired cases

δ 1,δ 2

0.5, 0.25

0.5, 0.25

Fraction of colonized inpatients placed in preemptive isolation

0

1

Discharge rates of susceptible, colonized and isolated patients

μ S,μ C,μ I

0.2, 0.2, 0.13

0.18, 0.18, 0.13

Number of patients

N

16

16

Number of isolation beds

N I

16

8

  1. Parameters in boldface were estimated from data using the iterated filtering algorithm, as explained in the main text. For these parameters, the maximum likelihood estimates (95% confidence intervals) are indicated. Rates are day–1.