Table 7 Sensitivity analysis results

Unfavourable scenario

 Avoided hospitalized pneumonias

785

3,749

8,690

14,925

21,993

50,141

 Avoided outpatient pneumonias

528

2,520

5,841

10,033

14,784

33,707

 Avoided primary bacteremias

21

102

208

398

503

1,232

 Avoided empyemas

0

1

3

5

7

17

 Avoided meningitis

7

34

69

131

166

406

 Avoided bacteremic pneumonias

49

237

484

924

1,169

2,863

 Avoided contagions

1,390

6,643

15,294

26,417

38,621

88,366

 Hospitalized pneumonia cost savings

1,400,564

6,691,314

15,508,174

26,637,024

39,250,376

89,487,451

 Outpatient pneumonia cost savings

118,698

567,092

1,314,325

2,257,501

3,326,488

7,584,104

 Primary bacteremias cost savings

78,398

374,823

766,424

1,464,809

1,852,303

4,536,757

 Empyemas cost savings

1,549

7,405

15,141

28,937

36,592

89,623

 Meningitis cost savings

70,727

338,147

691,432

1,321,482

1,671,060

4,092,848

 Bacteremic pneumonias cost savings

241,340

1,153,848

2,359,348

4,509,247

5,702,099

13,965,882

 Savings by all cases averted

1,911,277

9,132,628

20,654,844

36,218,999

51,838,917

119,756,665

 Cost of vaccinations

13,878,696

13,878,696

13,878,696

13,878,696

13,878,696

69,393,481

 Net healthcare cost

11,967,420

4,746,068

−6,776,147

−22,340,303

−37,960,221

−50,363,184

 Discounted net healthcare cost

11,967,420

4,520,065

−6,146,165

−19,298,394

−31,229,968

−40,187,043

Favourable scenario

 Avoided hospitalized pneumonias

1,744

8,632

18,959

29,239

38,179

96,754

 Avoided outpatient pneumonias

1,172

5,803

12,745

19,656

25,666

65,042

 Avoided primary bacteremias

47

234

454

779

873

2,387

 Avoided empyemas

1

3

6

11

12

32

 Avoided meningitis

16

77

150

257

288

787

 Avoided bacteremic pneumonias

110

545

1,055

1,811

2,029

5,550

 Avoided contagions

3,090

15,294

33,369

51,753

67,047

170,552

 Hospitalized pneumonia cost savings

3,804,001

18,829,047

41,355,130

63,780,008

83,280,575

211,048,761

 Outpatient pneumonia cost savings

322,391

1,595,771

3,504,867

5,405,386

7,058,069

17,886,484

 Primary bacteremias cost savings

212,934

1,054,733

2,043,798

3,507,357

3,930,174

10,748,996

 Empyemas cost savings

4,206

20,836

40,375

69,287

77,640

212,345

 Meningitis cost savings

192,099

951,530

1,843,818

3,164,172

3,545,617

9,697,236

 Bacteremic pneumonias cost savings

655,491

3,246,874

6,291,595

10,769,994

12,098,587

33,089,542

 Savings by all cases averted

5,191,122

25,698,792

55,079,583

86,723,204

109,990,663

282,683,364

 Cost of vaccinations

18,504,928

18,504,928

18,504,928

18,504,928

18,504,928

92,524,641

 Net healthcare cost

13,313,807

−7,193,863

−36,574,655

−68,218,276

−91,485,735

−190,158,723

 Discounted net healthcare cost

13,313,807

−7,193,863

−36,574,655

−68,218,276

−91,485,735

−190,158,723