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Table 4 Diagnosis accuracy of serum PCT, CRP, WBC, body temperature, ΔCRP and ΔPCT for diagnosis of ICU-acquired infection

From: A composite score combining procalcitonin, C-reactive protein and temperature has a high positive predictive value for the diagnosis of intensive care-acquired infections

 

AUC

Cut-off level

Sensitivity (%)

Specificity (%)

PPV

NPV

PCT D0

0.84

1.86 ng/mL

68

91

68

91

CRP D0

0.88

88 mg/L

92

70

47

97

WBC D0

0.62

12120/mm3

64

68

36

87

Temperature D0

0.88

38.6°C

76

94

79

94

Composite score D0

0.90

28

80

97

87

94

ΔPCT

0.83

0.49 ng/mL

68

94

77

91

ΔCRP

0.85

12 mg/L

92

71

48

97

  1. Data are presented as % unless otherwise stated. AUC: area under the receiver-operating-characteristic curve; NPV: negative predictive value; PPV: positive predictive value.