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Table 2 Renal function at the start of therapy

From: Evaluation of intravenous voriconazole in patients with compromised renal function

Parameter

Voriconazole

Caspofungin

Fluconazole

p-value for overall difference

Baseline Scr (mg/dL)

2.1 (0.9)

2.8 (1.5)

2.2 (1.3)

0.04

Baseline BUN (mg/dL)

33.3 (31.9)

56.5 (39.8)

48.7 (28.7)

0.04

Baseline Clcr (mL/min)

    

Cockcroft-Gault method

33.9 (9.0)

28.2 (12.0)

30.4 (10.3)

0.14

MDRD1 calculation

33.3 (14.0)

28.4 (17.1)

32.1 (15.5)

0.36

  1. 1Modification of Diet in Renal Disease.