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Table 2 The Xpert MTB/RIF test evaluation among children with suspected pulmonary TB (N = 235)

From: Evaluation of the Xpert MTB/RIF test for the diagnosis of childhood pulmonary tuberculosis in Uganda: a cross-sectional diagnostic study

 

Overall (n = 235)

HIV positive (n = 99)

HIV negative (n = 136)

 

Estimate

95% CI

Estimate

95% CI

Estimate

95% CI

Sensitivity (%)

27/34, 79.4

63.2 - 89.7

9/11,81.8

52.3-94.9

18/23, 78.3

58.1-90.3

Specificity (%)

194/201, 96.5

93- 98.3

84/88,95.5

88.9- 98.2

110/113, 97.4

92.5- 99.1

PPV (%)

79.4

63.2- 89.7

69.2

42.4- 87.3

85.7

65.4- 95

NPV (%)

96.2

93-98.3

97.7

91.9-99.4

95.7

90.2- 98.1

Diagnostic accuracy (%)

94

90.3- 96.4

93.9

87.4-97.2

94.1

88.8- 97

Likelihood ratio (+)

22.8

16.9 - 30.7

18

10.5 - 30.8

29.5

14.9- 58.4

Likelihood ratio (-)

0.2

0.2- 0.3

0.2

0.1-0.5

0.2

0.2 - 0.3

  1. PPV – Positive Predictive Value; NPV – Negative Predictive Value.