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Table 4 M. tuberculosis Haarlem lineage and its association with anti-tuberculosis drug resistance

From: Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia

Drug resistance

M. tuberculosislineages

OR (95% CI)

P-value*

 

Haarlem (n)

Non Haarlem (n)

  

Isoniazid

    

R

7

27

3.6 (1.3-9.8)

0.017

S

14

196

1

 

Rifampicin

    

R

7

7

15.4 (4.7-50.2)

<0.001

S

14

216

1

 

Streptomycin

    

R

6

20

4.1 (1.4-11.6)

0.015

S

15

203

1

 

Ethambutol

    

R

6

12

7.0(2.3-21.4)

0.002

S

15

211

1

 

Pyrazinamid

    

R

5

7

9.6 (2.7-33.8)

0.002

S

16

216

1

 

MDR-TB

    

Yes

7

5

21.8 (6.1-77.5)

<0.001

No

14

218

1

 

Resistant to all FLD

    

Yes

4

5

10.3 (2.5-41.8)

0.004

No

17

218

1

 
  1. R = resistant, S = sensitive, n = number, * = Fisher exact test, FLD = First line anti-TB drugs, MDR-TB = multidrug resistant tuberculosis.