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Table 4 M. tuberculosis Haarlem lineage and its association with anti-tuberculosis drug resistance

From: Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia

Drug resistance M. tuberculosislineages OR (95% CI) P-value*
  Haarlem (n) Non Haarlem (n)   
Isoniazid     
R 7 27 3.6 (1.3-9.8) 0.017
S 14 196 1  
Rifampicin     
R 7 7 15.4 (4.7-50.2) <0.001
S 14 216 1  
Streptomycin     
R 6 20 4.1 (1.4-11.6) 0.015
S 15 203 1  
Ethambutol     
R 6 12 7.0(2.3-21.4) 0.002
S 15 211 1  
Pyrazinamid     
R 5 7 9.6 (2.7-33.8) 0.002
S 16 216 1  
MDR-TB     
Yes 7 5 21.8 (6.1-77.5) <0.001
No 14 218 1  
Resistant to all FLD     
Yes 4 5 10.3 (2.5-41.8) 0.004
No 17 218 1  
  1. R = resistant, S = sensitive, n = number, * = Fisher exact test, FLD = First line anti-TB drugs, MDR-TB = multidrug resistant tuberculosis.