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Table 3 Anti-TB drug resistance, patients’ history of previous TB treatment and HIV status stratified for M. tuberculosis lineages

From: Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia

M. tuberculosislineages (n)

Anti-TB drugs resistance

PT N (%)

HIV + N (%)

 

INH N (%)

RMP N (%)

STM N (%)

EMB N (%)

PZA N (%)

MDR N (%)

RFLD N (%)

  

Dehli/CAS (95)

10(10.0)

3(3.3)

10(10.5)

7(7.4)

2 (2.1)

2 (2.1)

2 (2.1)

19 (20.0)

24(25.3)

Ethiopia_3 (32)

10(31.0)

3(9.4)

6(18.8)

5(15.6)

4 (12.5)

3(9.4)

3(9.4)

7(21.9)

4(12.5)

Haarlem (21)

7(33.33)

7(33.3)

6(28.6)

6(28.6)

5 (23.8)

7 (33.3)

4 (19.0)

2(9.5)

7(33.3)

Ethiopia_1 (19)

1 (5.3)

0

1(5.3)

0

1(5.3)

0

0

5 (26.3)

4(21.1)

Ethiopia_H37Rv like (17)

2(11.8)

0

1(5.9)

0

0

0

0

3(17.6)

6(35.3)

Ethiopia_2 (9)

0

0

0

0

0

0

0

1(11.1)

1(11.1)

URAL (8)

0

0

0

0

0

0

0

0

3 (37.5)

LAM (8)

0

0

0

0

0

0

0

0

2 (25.0)

TUR (5)

2 (40.0)

0

1(20.0)

0

0

0

0

1(20.0)

2 (40.0)

X-type (3)

1(33.3)

0

1(33.3)

0

0

0

0

0

2(66.7)

S-type (2)

0

0

0

0

0

0

0

0

0

Beijing (1)

0

0

0

0

0

0

0

0

0

UgandII (1)

0

0

0

0

0

0

0

0

0

Not defined (23)

1 (4.3)

1(4.3)

0

0

0

0

0

5(21.7)

7(30.4)

Total (244)

34 (13.9)

14(5.7)

26(10.7)

18 (7.4)

12 (4.9)

12 (4.9)

9(3.7)

43(17.6)

62(25.4)

  1. N= number, RFLD= Resistant to all first line anti-TB drugs, MDR= Multidrug resistant, LAM= M. tuberculosis Latin American Mediterranean, PT= previously treated cases, INH=isoniazid, RMP=rifampicin, STM= streptomycin, EMB= ethambutol, PZA= pyrazinamid, + = positive.