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Table 2 Discriminatory capacities of spoligotyping and MIRU-VNTR 24-loci, alone or in combination for M. tuberculosis isolates from Ethiopia

From: Molecular epidemiology and transmission dynamics of Mycobacterium tuberculosis in Northwest Ethiopia: new phylogenetic lineages found in Northwest Ethiopia

Genotyping method No. of different patterns No. of isolates with unique pattern No. of clusters No. of isolates in clusters Clustering rate (%) RTI (%) HGDI
Spoligotyping 69 43 26 201 82.4 64.8 0.88
MIRU-VNTR 24-loci 161 124 37 120 49.2 34.0 0.97
MIRU-VNTR 24-loci + Spoligotyping 170 134 36 110 45.1 30.3 0.97
  1. HGDI= Hunter-Gastone discriminatory index, highest degree for HGDI is 1 that shows highest discriminatory power of a method, RTI= Recent transmission index.