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Table 2 Characteristics of patients with laboratory-confirmed pertussis, M. pneumoniae , C. pneumoniae , viruses and mixed-pertussis infection with other pathogens

From: Diagnostic value of symptoms and laboratory data for pertussis in adolescent and adult patients

Characteristics Pertussis M. pneumoniae C. pneumoniae Viruses Mixed-pertussis infection*
Number 183 105 93 52 10
Age mean (range), years 39.1 (16–77) 35.2 (16–46) 36.4 (18–52) 39.4 (24–76) 39.7 (27–65)
Male : Female 73 : 110 49 : 56 45 : 48 25 : 27 5 : 5
Symptom**      
  Paroxysmal cough 165 (90.1) 89 (84.7) 68 (73.1)*** 24 (46.1)*** 100 (100.0)
  Awakened by cough 133 (72.6) 84 (80.0) 66 (70.9) 29 (55.7)*** 9 (90.0)
  Sputum production 67 (36.6) 40 (38.0) 30 (32.2) 17 (32.6) 5 (50.0)
  Chest pain 66 (36.0) 38 (36.1) 25 (26.8) 12 (23.0) 3 (30.0)
  Dyspnea 56 (30.6) 30 (28.5) 21 (22.5) 6 (11.5)*** 4 (40.0)
  Posttussive vomiting 46 (25.1) 20 (19.0) 15 (16.1) 0 *** 2 (20.0)
  Posttussive gagging 90 (49.1) 32 (30.4)*** 22 (23.6)*** 6 (11.5)*** 6 (60.0)
  Inspiratory whoop 36 (19.6) 11 (10.4)*** 10 (10.7)*** 0*** 1 (10.0)
  History of fever (≥37.0°C) 27 (14.7) 35 (33.3)*** 8 (8.6) 19 (36.5)*** 50 (50.0)***
Upper respiratory tract infection symptoms before cough 83 (45.3) 55 (52.3) 37 (39.7) 45 (86.5)*** 8 (80.0)***
Exposed to cough by family member or work/school colleague** 97 (53.0) 49 (46.6) 40 (43.0) 26 (50.0) 60 (60.0)
Hospitalization** 1 (0.5) 1 (0.9) 0 0 1 (10.0)
Laboratory data      
  WBC mean number ± SD, /mm3 6,619 ± 2,815 6,249 ± 2,731 6,972 ± 2,618 6,314 ± 2,765 6,898 ± 2,265
Lymphocyte mean number ± SD, /mm3 2,043 ± 892 1,986 ± 878 2,361 ± 958 2,419 ± 954 2,133 ± 854
  1. * Mixed-pertussis infection with other pathogens: Chlamydophila pneumoniae (one case), Mycoplasma pneumoniae (one case), Streptococcus pneumoniae (one cases), Moraxella catarrhalis (one case) and viruses (six cases).
  2. ** Data represent the numbers (%) of patients.
  3. *** When compared to patients with laboratory-confirmed pertussis, the differences were significant (p-value indicate <0.05).