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Table 2 Characteristics of patients with laboratory-confirmed pertussis, M. pneumoniae , C. pneumoniae , viruses and mixed-pertussis infection with other pathogens

From: Diagnostic value of symptoms and laboratory data for pertussis in adolescent and adult patients

Characteristics

Pertussis

M. pneumoniae

C. pneumoniae

Viruses

Mixed-pertussis infection*

Number

183

105

93

52

10

Age mean (range), years

39.1 (16–77)

35.2 (16–46)

36.4 (18–52)

39.4 (24–76)

39.7 (27–65)

Male : Female

73 : 110

49 : 56

45 : 48

25 : 27

5 : 5

Symptom**

     

  Paroxysmal cough

165 (90.1)

89 (84.7)

68 (73.1)***

24 (46.1)***

100 (100.0)

  Awakened by cough

133 (72.6)

84 (80.0)

66 (70.9)

29 (55.7)***

9 (90.0)

  Sputum production

67 (36.6)

40 (38.0)

30 (32.2)

17 (32.6)

5 (50.0)

  Chest pain

66 (36.0)

38 (36.1)

25 (26.8)

12 (23.0)

3 (30.0)

  Dyspnea

56 (30.6)

30 (28.5)

21 (22.5)

6 (11.5)***

4 (40.0)

  Posttussive vomiting

46 (25.1)

20 (19.0)

15 (16.1)

0 ***

2 (20.0)

  Posttussive gagging

90 (49.1)

32 (30.4)***

22 (23.6)***

6 (11.5)***

6 (60.0)

  Inspiratory whoop

36 (19.6)

11 (10.4)***

10 (10.7)***

0***

1 (10.0)

  History of fever (≥37.0°C)

27 (14.7)

35 (33.3)***

8 (8.6)

19 (36.5)***

50 (50.0)***

Upper respiratory tract infection symptoms before cough

83 (45.3)

55 (52.3)

37 (39.7)

45 (86.5)***

8 (80.0)***

Exposed to cough by family member or work/school colleague**

97 (53.0)

49 (46.6)

40 (43.0)

26 (50.0)

60 (60.0)

Hospitalization**

1 (0.5)

1 (0.9)

0

0

1 (10.0)

Laboratory data

     

  WBC mean number ± SD, /mm3

6,619 ± 2,815

6,249 ± 2,731

6,972 ± 2,618

6,314 ± 2,765

6,898 ± 2,265

Lymphocyte mean number ± SD, /mm3

2,043 ± 892

1,986 ± 878

2,361 ± 958

2,419 ± 954

2,133 ± 854

  1. * Mixed-pertussis infection with other pathogens: Chlamydophila pneumoniae (one case), Mycoplasma pneumoniae (one case), Streptococcus pneumoniae (one cases), Moraxella catarrhalis (one case) and viruses (six cases).
  2. ** Data represent the numbers (%) of patients.
  3. *** When compared to patients with laboratory-confirmed pertussis, the differences were significant (p-value indicate <0.05).