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Table 1 Baseline clinical features of children with malaria

From: Endotoxaemia is common in children with Plasmodium falciparummalaria

 

Non-severe malaria

Severe malaria

Severe malaria & shock

P

Age (months) a

30.2 (15.5-52.8)

32.5 (14.8-57.6)

31.9 (14.8-48.2)

0.726

Impaired perfusion b

31.4% (16/51)

-

100% (154/154)

<0.0001

Respiratory distress b

-

71.2% (37/52)

83.1% (128/154)

0.049

Impaired consciousness b

-

36.5% (19/52)

71.4% (110/154)

<0.0001

Coma b

-

9.6% (5/52)

20.8% (32/154)

0.067

Severe anaemia b

-

11.8% (6/51)

34.7% (52/150)

0.002

Mortality (48 h) b

-

0% (0/52)

6.5% (10/154)

-

Endotoxaemia (EAA≥0.4) b

31.4% (16/51)

28.3% (15/52)

26.0% (40/154)

0.738

High endotoxaemia (EAA≥0.6) b

9.8% (5/51)

5.8% (3/52)

10.4% (16/154)

0.608

  1. a Shown are median and in parenthesis 25th and 75th percentile. For comparison of difference in age between groups, Kruskal-Wallis H test was used.
  2. b Percentage of children presenting with syndrome and in parenthesis the number of children presenting with a syndrome over the total number of children in that group. For comparison of the proportion of children presenting with a given syndrome, Pearson χ2 was used.