Skip to main content

Table 2 Clinical features of patients with acute bacterial meningitis according to age group*

From: The spectrum of acute bacterial meningitis in elderly patients

 

Group I (non-elderly)

Group II (elderly)

RR (95% CI)

P value

 

N = 427

N = 208

  

Interval symptoms-admission (hrs)

24.0 (24.0–37.0)

27.5 (24.0–37.0)

----

0.3822

Prior antimicrobial therapy (%)

126 (29.5)

77 (37.0)

1.25 (1.00–1.57)

0.0696

Extrameningeal infection† (%)

96 (22.5)

79 (37.9)

1.61(1.29–2.00)

< 0.0001

Pneumonia (%)

17 (4.0)

20 (9.6)

1.72 (1.25–2.37)

0.0077

ENT infection (%)

56 (8.8)

33 (5.2)

1.16 (0.86–1.56)

0.4149

Urinary tract infection (%)

9 (1.4)

18 (2.8)

2.13 (1.59–2.86)

0.0003

Fever (%)

412 (96.5)

193 (92.8)

0.64 (0.44–0.93)

0.0625

Level of consciousness (%)

    

Normal (%)

174 (40.7)

49 (23.6)

0.57 (0.43–0.75)

< 0.0001

Abnormal (%)

229 (62.6)

142 (68.3)

1.53 (1.20–1.93)

0.0006

Coma (%)

24 (5.6)

17 (8.2)

1.39 (0.95–2.04)

0.1639

Neck stiffness (%)

357 (83.6)

129 (62.0)

0.50 (0.41–0.62)

< 0.0001

Meningeal triad present (%)

208 (48.7)

104 (50.0)

1.04 (0.83–1.29)

0.8275

Skin rash (%)

153 (35.8)

19 (9.1)

0.27 (0.17–0.62)

< 0.0001

Interval admission-therapy (hrs)

3.0 (1.0–6.0)

4.0 (2.0–12.0)

----

< 0.0001

Focal neurologic signs on admission (%)

63 (14.7)

43 (20.7)

1.30 (1.00–1.69)

0.0777

Seizures on admission (%)

33 (7.7)

13 (6.2)

0.85 (0.53–1.37)

0.6091

Cerebral computed tomography (%)

163 (57.8)

113 (75.8)

1.55 (1.24–1.93)

0.0002

  1. Values expressed as median and interquartile range unless otherwise specified. ENT = ear, nose and throat. *A patient may have more than an extrameningeal focus of infection. † Includes: otiitis (73), pneumonia (37), urinary tract infection (27), paranasal sinusitis (23), endocarditis (7), pyelonephritis (4), acute bronchitis (4), tonsillitis (3), parappharyngeal abscess (2), cholecystitis (2), peritonitis (2), ventriculo-peritoneal shunt (2), dental abscess (2), scrotal abscess (1), psoas abscess (1), i.v. catheter (1), pacemaker electrode infection (1).