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Table 3 Comparison by age group of the outcome in 633 adults admitted to hospital with non-typhoidal Salmonella gastroenteritis in Liverpool between 1982 and 2006 inclusive

From: A retrospective study of secondary bacteraemia in hospitalised adults with community acquired non-typhoidal Salmonella gastroenteritis

  All patients Age < 65 years with no underlying chronic disease Age < 65 years with underlying chronic disease p1 Age ≥ 65 years with no underlying chronic disease Age ≥ 65 years with underlying chronic disease P2
Number 633 381 102   50 100  
Bacteremia 63/364 (17.3) 24/225 (10.7) 12/63 (19.0) 0.086 10/26 (38.5) 17/50 (34.0) 0.802
Given intravenous fluids 367 (58.0) 206 (54.1) 63 (61.8) 0.790 34 (68.0) 64 (64.0) 0.717
Given antibiotic in hospital 286 (45.2) 155 (40.7) 45 (44.1) 0.572 25 (50.0) 61 (61.0) 0.223
All complications 148 (23.4) 54 (14.2) 22 (21.6) 0.095 22 (44.0) 50 (50.0) 0.603
Specific complications 3        
Duration of admission > 21 days 66 (10.4) 14 (3.7) 11 (10.8) 0.009 12 (24.5) 30 (30.0) 0.563
Gastrointestinal complication 4 44 (7.0) 21 (5.5) 10 (9.8) 0.169 1 (2.0) 12 (12.0) 0.061
Renal impairment 26 (4.1) 4 (1.0) 6 (5.9) 0.008 8 (16.0) 8 (8.0) 0.163
Urinary tract infection 15 (2.4) 10 (2.6) 0 (0) 0.130 0 (0) 5 (5.0) 0.170
Pneumonia 14 (2.2) 2 (0.5) 2 (2.0) 0.198 3 (6.0) 7(7.0) 1.00
Hypotension 13 (2.1) 3 (1.0) 4 (4.0) 0.039 2 (4.0) 4 (4.0) 1.00
Reactive arthritis/uveitis 9 (1.4) 8 (2.1) 1 (1.0) 0.692 0 (0) 0 (0) -
Central nervous complication5 5 (0.8) 0 (0) 2 (2.0) 0.044 2 (4.0) 1 (1.0) 0.258
Vascular complication6 4 (0.6) 0 (0) 0 (0) - 1 (2.0) 3 (3.0) 1.00
Total deaths 14 (2.2) 0 (0) 1 (1.0) 0.211 1 (2.0) 12 (12.0) 0.061
Attributable deaths 9 (1.4) 0 (0) 1(1.0) 0.211 1 (2.0) 7 (7.0) 0.270
  1. Data are number (%), except where stated.
  2. 1 Univariate statistical comparison of those age < 65 with no underlying disease versus age < 65 with underlying disease.
  3. 2 Univariate statistical comparison of those age ≥ 65 with no underlying disease versus age ≥ 65 with underlying disease.
  4. 3 14 patients with site specific complications had more than one site affected.
  5. 4 Ileus/subacute obstruction (7); severe colitis (7); prolonged diarrhoea (diarrhoea persisting for > two weeks) (6); irritable bowel syndrome (5); Clostridium difficile colitis (3); appendicitis (2); recurrent diarrhoea (recurrence of diarrhoea after intial recovery) (2); toxic colonic dilatation (2); erosive gastritis (1); exacerbation of pre-existing inflammatory bowel disease (1); gastrointestinal bleeding (1); persistent vomiting (1).
  6. 5 Acute confusion (3), coma with possible encephalopathy (2).
  7. 6 Cerebrovascular accident (2); pulmonary embolus, gangrene and cerebrovascular accident (1); septic thrombophlebitis (1).