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Table 3 Comparison by age group of the outcome in 633 adults admitted to hospital with non-typhoidal Salmonella gastroenteritis in Liverpool between 1982 and 2006 inclusive

From: A retrospective study of secondary bacteraemia in hospitalised adults with community acquired non-typhoidal Salmonella gastroenteritis

 

All patients

Age < 65 years with no underlying chronic disease

Age < 65 years with underlying chronic disease

p1

Age ≥ 65 years with no underlying chronic disease

Age ≥ 65 years with underlying chronic disease

P2

Number

633

381

102

 

50

100

 

Bacteremia

63/364 (17.3)

24/225 (10.7)

12/63 (19.0)

0.086

10/26 (38.5)

17/50 (34.0)

0.802

Given intravenous fluids

367 (58.0)

206 (54.1)

63 (61.8)

0.790

34 (68.0)

64 (64.0)

0.717

Given antibiotic in hospital

286 (45.2)

155 (40.7)

45 (44.1)

0.572

25 (50.0)

61 (61.0)

0.223

All complications

148 (23.4)

54 (14.2)

22 (21.6)

0.095

22 (44.0)

50 (50.0)

0.603

Specific complications 3

       

Duration of admission > 21 days

66 (10.4)

14 (3.7)

11 (10.8)

0.009

12 (24.5)

30 (30.0)

0.563

Gastrointestinal complication 4

44 (7.0)

21 (5.5)

10 (9.8)

0.169

1 (2.0)

12 (12.0)

0.061

Renal impairment

26 (4.1)

4 (1.0)

6 (5.9)

0.008

8 (16.0)

8 (8.0)

0.163

Urinary tract infection

15 (2.4)

10 (2.6)

0 (0)

0.130

0 (0)

5 (5.0)

0.170

Pneumonia

14 (2.2)

2 (0.5)

2 (2.0)

0.198

3 (6.0)

7(7.0)

1.00

Hypotension

13 (2.1)

3 (1.0)

4 (4.0)

0.039

2 (4.0)

4 (4.0)

1.00

Reactive arthritis/uveitis

9 (1.4)

8 (2.1)

1 (1.0)

0.692

0 (0)

0 (0)

-

Central nervous complication5

5 (0.8)

0 (0)

2 (2.0)

0.044

2 (4.0)

1 (1.0)

0.258

Vascular complication6

4 (0.6)

0 (0)

0 (0)

-

1 (2.0)

3 (3.0)

1.00

Total deaths

14 (2.2)

0 (0)

1 (1.0)

0.211

1 (2.0)

12 (12.0)

0.061

Attributable deaths

9 (1.4)

0 (0)

1(1.0)

0.211

1 (2.0)

7 (7.0)

0.270

  1. Data are number (%), except where stated.
  2. 1 Univariate statistical comparison of those age < 65 with no underlying disease versus age < 65 with underlying disease.
  3. 2 Univariate statistical comparison of those age ≥ 65 with no underlying disease versus age ≥ 65 with underlying disease.
  4. 3 14 patients with site specific complications had more than one site affected.
  5. 4 Ileus/subacute obstruction (7); severe colitis (7); prolonged diarrhoea (diarrhoea persisting for > two weeks) (6); irritable bowel syndrome (5); Clostridium difficile colitis (3); appendicitis (2); recurrent diarrhoea (recurrence of diarrhoea after intial recovery) (2); toxic colonic dilatation (2); erosive gastritis (1); exacerbation of pre-existing inflammatory bowel disease (1); gastrointestinal bleeding (1); persistent vomiting (1).
  6. 5 Acute confusion (3), coma with possible encephalopathy (2).
  7. 6 Cerebrovascular accident (2); pulmonary embolus, gangrene and cerebrovascular accident (1); septic thrombophlebitis (1).