Table 1 Preliminary evaluation: performance of three syphilis serological assays using Dried Blood Spots compared to plasma
Plasma as reference (using the same assay) | Positive samples detected | Negative samples detected | Sensitivity (95% CI)* | Specificity (95% CI)* |
|---|---|---|---|---|
DBS TPPA † (n=463) | 82/96 | 363/367 | 85.4% | 98.9% |
(76.7–91.8%) | (97.2–99.7%) | |||
DBS EIA (n=282) | 53/56 | 114/226 | 94.6% | 50.4% |
(85.1–98.9%) | (43.7–57.1%) | |||
DBS TPHA ‡ (n=445) | 46/91 | 353/354 | 50.5% | 99.7% |
(39.9–61.2%) | (98.4–100%) |