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Table 3 Rates of antiviral administration (mean and 95% confidence intervals) among laboratory-confirmed A/H1N1 influenza cases by pandemic wave, Mexico, 01 April through 31 December, 2009

From: Impact of antiviral treatment and hospital admission delay on risk of death associated with 2009 A/H1N1 pandemic influenza in Mexico

Variable Total A/H1N1 cases Pandemic wave P valuea
   Wave 1 Wave 2 Wave 3  
No. patients that received antivirals (% of total A/H1N1 cases) 19.3% (18.8, 19.7) 48.6% (44.6,52.6) 54.9% (53.6,56.2) 8.7% (8.32,9.09) P < 0.0001
Geographic
Central 12.1% (11.5,12.7) 41.6% (36.9,46.4) 38.5% (34.6,42.6) 9.19% (8.63,9.78) P < 0.0001
Southern 39.1% (37.9,40.4) 65.5% (51.9,77.5) 59.8% (58.3,61.4) 5.13% (4.27,6.11) P < 0.0001
Other states 15.2% (14.5,15.9) 65.3% (56.3,73.6) 48.8% (46.2,51.5) 9.08% (8.48,9.7) P < 0.0001
Female 19.4% (18.8,20.1) 47.7% (42.1,53.5) 53.8% (52,55.6) 9.33% (8.79,9.9) P < 0.0001
Male 19% (18.4,19.7) 49.5% (43.8,55.3) 56.1% (54.2,57.9) 8.03% (7.51,8.57) P < 0.0001
Age (years)
<18 19.5% (18.9,20.2) 50.2% (44.2,56.2) 58.2% (56.5,60) 7.09% (6.59,7.6) P < 0.0001
18–49 19.8% (19.1,20.5) 48.2% (42.3,54.2) 52.4% (50.4,54.4) 10.4% (9.79,11) P < 0.0001
>50 14.2% (12.7,15.9) 43.1% (29.3,57.8) 40% (34,46.2) 8.99% (7.61,10.5) P < 0.0001
Patients according to severity  
Outpatients 20.1% (19.6,20.7) 48.7% (44,53.4) 55.4% (54,56.7) 8.67% (8.25,9.09) P < 0.0001
Inpatients 14.6% (13.4,15.8) 46.6% (37.8,55.5) 49.4% (43.9,54.9) 9.29% (8.26,10.4) P < 0.0001
Deaths 11.1% (8.68,13.9) 57.1% (37.2,75.5) 39% (24.2,55.5) 6.4% (4.44,8.86) P < 0.0001
  1. Wave 1 (spring) refers to April 1 through May 20; wave 2 (summer) refers to May 21 through August 1; wave 3 (fall) refers to August 2 through December 31 of 2009.
  2. a Determined by the Chi-square test statistic.