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Table 3 Interactions between prognostic factors and calendar periods in the German HIV-1 Seroconverter Cohort, 2010

From: The risk of AIDS-defining events is decreasing over time in the German HIV-1 Seroconverter Cohort

    

Calendar periods

  

P-value for interaction

  

pre-1997

 

1997-2007

 

2007-2010

 
 

HR†

95% CI

HR†

95% CI

HR†

95% CI

 

Sex, female

1.0

0.2-4.6

1.7

0.8 3.7

0.7

0.1 4.5

0.6509

Age (per 10years increase in age)

1.6

1.1-2.2

1.4

1.2 - 1.8

1.0

0.8 - 1.4

0.1287

HIV exposure category

       

men who have sex with men

1

1

1

    

Injecting drug users

0.8

0.3 - 2.6

1.9

0.9 4.1

1.4

0.2 11.1

0.5575

heterosexuals

0.2

0.04 - 1.4

1.1

0.5 - 2.4

0.5

0.1 - 2.1

 

people from high endemic country

2.7

0.6 12.7

2.1

0.7 - 7.0

1.6

0.2 13.8

 

Short HIV test interval*

1.4

1.0 1.9

1.1

0.7 - 1.8

1.7

1.0 2.8

0.3956

  1. *defined as 3months between last negative and first positive HIV test, or with laboratory evidence of seroconversion.
  2. †To ease the interpretation we show all hazard ratios in comparison to the MSM risk of the respective calendar period.
  3. HR: Hazard Ratio; CI, confident interval.