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Table 3 Interactions between prognostic factors and calendar periods in the German HIV-1 Seroconverter Cohort, 2010

From: The risk of AIDS-defining events is decreasing over time in the German HIV-1 Seroconverter Cohort

     Calendar periods    P-value for interaction
   pre-1997   1997-2007   2007-2010  
  HR† 95% CI HR† 95% CI HR† 95% CI  
Sex, female 1.0 0.2-4.6 1.7 0.8 3.7 0.7 0.1 4.5 0.6509
Age (per 10years increase in age) 1.6 1.1-2.2 1.4 1.2 - 1.8 1.0 0.8 - 1.4 0.1287
HIV exposure category        
men who have sex with men 1 1 1     
Injecting drug users 0.8 0.3 - 2.6 1.9 0.9 4.1 1.4 0.2 11.1 0.5575
heterosexuals 0.2 0.04 - 1.4 1.1 0.5 - 2.4 0.5 0.1 - 2.1  
people from high endemic country 2.7 0.6 12.7 2.1 0.7 - 7.0 1.6 0.2 13.8  
Short HIV test interval* 1.4 1.0 1.9 1.1 0.7 - 1.8 1.7 1.0 2.8 0.3956
  1. *defined as 3months between last negative and first positive HIV test, or with laboratory evidence of seroconversion.
  2. †To ease the interpretation we show all hazard ratios in comparison to the MSM risk of the respective calendar period.
  3. HR: Hazard Ratio; CI, confident interval.