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Table 2 Rare nonsynonymous and synonymous variation of NOD2 gene in the cases and control

From: A novel single nucleotide polymorphism within the NOD2 gene is associated with pulmonary tuberculosis in the Chinese Han, Uygur and Kazak populations

Amino acid variation
(codon variation)
Case patients
n = 425
Control subjects
n = 380
OR
(95%CI)
P-value
Arg541Trp(CGG-TGG) 2 2   
Ala579Gly(GCC-GGC) 3 0   
Phe584Phe(TTC-TTT) 2 0   
Ala588Ala(GCG-GCA) 0 1   
Ala611Ala(GCC-GCT) 5 0   
Ala612Thr(GCG-ACG) 1 0   
Ala661Pro(GCT-CCT) 1 2   
Glu667Lys(GAG-AAG) 0 1   
Pro668Pro(CCG-CCT) 1 0   
Arg708His(CGC-CAC) 1 0   
Aal725Val(GCT-GTT) 0 1   
Pro727Pro(CCG-CCA) 1 0   
Total 17 7 2.220
(0.911-5.414)
0.072
  1. The total occurrences of rare nonsynonymous and synonymous polymorphisms were compared between case patients and control subjects by use of a χ 2 test for 2-by-2 contingency tables.
  2. CI, confidence interval; OR, odds ratio.