Table 2 Rare nonsynonymous and synonymous variation of NOD2 gene in the cases and control
Amino acid variation (codon variation) | Case patients n = 425 | Control subjects n = 380 | OR (95%CI) | P-value |
|---|---|---|---|---|
Arg541Trp(CGG-TGG) | 2 | 2 | ||
Ala579Gly(GCC-GGC) | 3 | 0 | ||
Phe584Phe(TTC-TTT) | 2 | 0 | ||
Ala588Ala(GCG-GCA) | 0 | 1 | ||
Ala611Ala(GCC-GCT) | 5 | 0 | ||
Ala612Thr(GCG-ACG) | 1 | 0 | ||
Ala661Pro(GCT-CCT) | 1 | 2 | ||
Glu667Lys(GAG-AAG) | 0 | 1 | ||
Pro668Pro(CCG-CCT) | 1 | 0 | ||
Arg708His(CGC-CAC) | 1 | 0 | ||
Aal725Val(GCT-GTT) | 0 | 1 | ||
Pro727Pro(CCG-CCA) | 1 | 0 | ||
Total | 17 | 7 | 2.220 (0.911-5.414) | 0.072 |