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Table 4 Univariate and multivariate analyses for factors associated with total seroconversion for 2009 pandemic influenza A (H1N1) in 90 unvaccinated healthcare workers at a children' hospital in Taiwan

From: Longitudinal seroepidemiologic study of the 2009 pandemic influenza A (H1N1) infection among health care workers in a children's hospital

Characteristics No. (median/mean) Crude OR (95% CI) P value Adjusted OR (95% CI) P value
Age per 10 years1 (29.2/31) 1.45 (0.71-2.93) 0.305   
Male sex 18 0.69 (0.14-3.45) 0.654   
Baseline anti-H1N1 titer2 (10.0/12.3) 0.36 (0.07-2.01) 0.245   
High risk group3 40 3.34 (0.94-11.80) 0.061 6.51 (1.13-37.52) 0.036
Optimal surgical mask usage 75 3.39E8 (0.00-∞) 0.998   
Optimal hand hygiene 83 3.00E8 (0.00-∞) 0.999   
ILI episode 21 12.19 (3.23-46.04) < 0.001 9.14 (2.02-41.36) 0.004
Virologically confirmed 2009 H1N1 infection4 9 11.41 (2.54-51.32) 0.002 5.99 (0.98-36.48) 0.052
  1. Abbreviations: OR, odds ratio; CI, confidence interval; ILI episode, influenza-like illness episode.
  2. 1 For every 10-year increase in age, for which integer values 0-3 denote ages of 20-30, 30-40, 40-50, and 50-60, respectively.
  3. 2 Unit increase in baseline titer, for which integer values 0-8 denote titers of < 10, 10, 20, 40, 80, 160, 320, 640, and 1280 or more, respectively.
  4. 3 HCWs in direct contact with patients with 2009 pandemic influenza A (H1N1) infection or their respiratory samples were designated high-risk group.
  5. 4 Virologically confirmed means either viral isolation or real time polymerase chain reaction was positive of 2009 H1N1 influenza virus.