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Table 1 Overview of patient characteristics

From: Diagnostic performance of line-immunoassay based algorithms for incident HIV-1 infection

A) Patients with incident infection (n = 527)
  ZPHI patients   HIV notifications  
Number 144   383  
   Male (n, %) 129 (89.6) 332 (86.7)
   Female (n, %) 15 (10.4) 51 (13.3)
Transmission risk (n, %)     
MSM 102 (70.8) 242 (63.2)
HET 37 (25.7) 102 (26.6)
IVDU 4 (2.8) 17 (4.4)
OTH 1 (0.7) 0 (0)
Unknown 0 (0) 22 (5.7)
Age (median, IQR) 36 (30 - 42) 35 (28 - 43)
Months of infection (median, IQR) 1.59 (1.05 - 2.73) 1.04 (0.33 - 3.0)
HIV-1 RNA, (log [copies/mL]), IQR 5.1 (4.5 - 5.8) 5.2 (4.5 - 6.1)
CD4+ T cell count, cells/μL (median, IQR) 372 (270 - 552) n.a.  
B) Patients with older infection (n = 740)
  SHCS patients*   HIV notifications  
Number 412   328  
   Male (n, %) 205 (49.8) 231 (70.4)
   Female (n, %) 207 (50.2) 97 (29.6)
Transmission risk (n, %)     
MSM 54 (13.1) 90 (27.4)
HET 283 (68.7) 194 (59.1)
IVDU 48 (11.6) 16 (4.9)
OTH 24 (6.6) 6 (1.8)
Unknown 0 (0) 21 (6.4)
Age (median, IQR) 35 (30 - 41) 44 (34 - 53)
Days of infection (median, IQR) n.a. n.a. n.a. n.a.
HIV-1 RNA, (log [copies/mL]), IQR 3.9 (2.9 - 4.7) 5.16 (4.8 - 5.6)
CD4+ T cell count, cells/μL (median, IQR) 350 (208 - 544) n.a.  
Treatment status     
   Prior to ART 190 (46.1) 328 (100)
   Under ART 222 (53.9) 0 (0)
C) Notifications with unknown duration of infection (n = 1374)
Number    1374  
Male (n, %)    924 (67.2)
Female (n, %)    423 (30.8)
Unknown    27 (2.0)
Transmission risk (n, %)     
MSM    401 (29.2)
HET    472 (34.3)
IVDU    40 (2.9)
OTH    8 (0.6)
Unknown    453 (33.0)
Age (median, IQR)    36 (30 - 45)
HIV-1 RNA, (log [copies/mL]), IQR    4.8 (4.1 - 5.4)
  1. n.a., not available; *same patients as investigated in [36]
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