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Table 2 Unitary costs* and treatment duration parameters used in the model; base-case and sensitivity analysis

From: Cost-effectiveness of posaconazole versusfluconazole or itraconazole in the prevention of invasive fungal infections among high-risk neutropenic patients in Spain

  Base-case estimate Sensitivity analysis   
    Deterministic   Probabilistic  
   Reference   Reference Distribution SD
Total treatment cost per day     
Posaconazole 103.69   77.77 - 129.61 Assum. Gamma 0.000
Fluconazole 16.93   12.70 - 21.16 Assum. Gamma 0.000
Itraconazole 21.85   16.39 - 27.31 Assum. Gamma 0.000
Drug cost per day      
Posaconazole 90.00 CGCOF[34]     
Fluconazole 8.00 CGCOF[34]     
Itraconazole 8.95 CGCOF[34]     
Preparation, administration and monitoring treatment cost per day   
Posaconazole 13.69 Gisbert[35]     
Fluconazole 8.93 Gisbert[35]     
Itraconazole 12.90 Gisbert[35]     
Treatment duration      
Posaconazole 29 Cornely[10]     
Fluconazole 24 Cornely[10]     
Itraconazole 29 Cornely[10]     
Cost of an invasive fungal infection (IFI)    
In-patient cost 67,984 Grau[36]* 50,988 - 84,980 Assum. Gamma  
  1. *In euros at November 2009 prices