Skip to main content

Table 1 Characteristics of study patients

From: Factors associated with delayed diagnosis of tuberculosis in hospitalized patients in a high TB and HIV burden setting: a cross-sectional study

Characteristics

Total

n = 305

Group 1 (≤ 6 d)

n = 166

Group 2 (> 6 d)

n = 139

p value*

Time until diagnosis (days)

6 (2-12)

2 (1 - 4)

12 (9 - 19)

-

Demographic characteristics

41.9 ± 17.4

40.3 ± 16.1

43.8 ± 18.7

0.079

Age, yr

    

Age > 60 years

40 (13.1)

17 (10.2)

25 (18.0)

0.051

Male sex

108 (35.4)

61 (37.7)

47 (33.8)

0.594

White race

230 (75.4)

123 (74.1)

107 (77.0)

0.560

Current smokers

91 (35.4)

56 (41.5)

35 (28.7)

0.032

Alcoholism

89 (29.2)

46 (27.9)

43 (30.9)

0.560

Injection drug use

81 (26.6)

50 (30.3)

31 (22.3)

0.116

Forms of TB

    

Isolated Pulmonary TB

110 (36.1)

77 (46.4)

33 (23.7)

< 0.0001

Isolated Extra-pulmonary TB

143 (46.9)

53 (31.9)

90 (64.7)

< 0.0001

Pulmonary + extra-pulmonary TB

52 (17.0)

36 (21.7)

16 (11.5)

0.019

Symptoms

    

Cough

132 (43.3)

89 (53.6)

43 (30.9)

< 0.0001

Night sweats

74 (24.3)

54 (32.5)

20 (14.4)

< 0.0001

Fever

190 (62.3)

111(66.9)

79 (56.8)

0.072

Laboratory results

    

Smear-negative sputum

93 (56.7)

45 (42.1)

48 (84.2)

< 0.0001

Radiographic patterns

    

Cavitary disease

33 (10.8)

28 (16.9)

5 (3.6)

< 0.0001

Pleural effusion

58 (19.0)

24 (14.5)

34 (24.5)

0.027

Miliary pattern

37 (12.1)

29 (17.5)

8 (5.8)

0.002

Consolidation

52 (17.0)

31 (18.7)

21 (15.1)

0.409

Normal

42 (13.8)

14 (8.4)

28 (20.1)

0.003

Previous default from TB treatment

24 (7.9)

20 (12.0)

4 (2.9)

0.003

Comorbidities

    

Presence of any comorbidity

224 (73.4)

130 (78.3)

94 (67.6)

0.035

HIV positive

191 (71.0)

117 (75.5)

74 (64.9)

0.059

Diabetes mellitus

19 (6.2)

3 (1.8)

16 (11.5)

< 0.0001

Chronic renal failure

8 (2.6)

1 (0.6)

7 (5.0)

0.016

Mechanical ventilation

48 (16.3)

28 (17.4)

20 (15.0)

0.587

In-hospital mortality

50 (16.4)

29 (17.5)

21 (15.1)

0.579

Mortality after discharge

47 (18.4)

22 (16.1)

25 (21.2)

0.292

  1. Continuous variables (age) are presented as mean ± SD; other data are presented as n/N (%): number of cases with characteristic/total number of cases (percentage in the group), or median (interquartile range)
  2. * p for the comparison between groups 1 and 2