Table 2 Nasopharyngeal carriage of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus in children with AOM before and after PCV7 implementation
Carriage | Before PCV7 n = 1807 (%) | After PCV7 n = 2598 (%) | p-value* |
|---|---|---|---|
S. pneumoniae | 1047 (57.9) | 1510 (58.1) | 0.9 |
PCV7 vaccine types | 402/604**(66.6) | 162 (10.7) | 0.0001 |
Penicillin intermediate- resistant | 317 (30.3) | 656 (43.4) | 0.0001 |
Penicillin resistant | 239 (22.8) | 58 (3.8) | 0.0001 |
Non-typable H. influenzae | 849 (47) | 1269 (48.8) | 0.2 |
ß-lactamase+ | 328 (38.6) | 217 (17.1) | 0.0001 |
M. catarrhalis | 939 (52) | 1479 (56.9) | 0.001 |
S. aureus | 112 (6.2) | 136 (5.2) | 0.2 |
Multiple carriage (≥ 2 species) | 978 (54.1) | 1502 (57.8) | 0.02 |
No carriage | 133 (7.4) | 187 (7.2) | 0.8 |