Table 1 Demographic and clinical characteristics of children with acute otitis media (AOM) before and after 7-valent pneumococcal conjugate vaccine (PCV7) implementation in France
Child characteristics | Before PCV7 n = 1.807 (%) | After PCV7 n = 2,598 (%) | p-value |
|---|---|---|---|
Male sex' | 970 (53.7) | 1,376 (53.0) | 0.6 |
Age (months), mean ± SD | 14.6 ± 7.6 | 13.8 ± 5.1 | < 0.0001 |
Median | 12.8 | 13.1 | |
Type of care | < 0.0001 | ||
Daycare center | 436 (24.1) | 1032 (39.7) | |
Child caregiver | 530 (29.3) | 811 (31.2) | |
Home | 841 (46.6) | 754 (29.1) | |
Antibiotics 3 months before enrolment | 336 (57.2)* | 1243 (47.9) | < 0.0001 |
Conjunctivitis | 436 (24.1) | 652 (25.1) | 0.5 |
Otalgia | 1304 (83.0)** | 1945 (75.0) | < 0.0001 |
Fever (≥ 38.5°C) | 671 (37.1) | 1551 (60.3) | < 0.0001 |