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Table 1 Sensitivity, specificity, positive predictive value and negative predictive value of MODS in detection of M.tuberculosis and INH or RIF resistance

From: Evaluation of microscopic observation drug susceptibility assay for diagnosis of multidrug-resistant Tuberculosis in Viet Nam

 

Sensitivity

% (n = x/y) 95%CI

Specificity

% (n = x/y) 95%CI

PPV

% (n = x/y) 95%CI

NPV

% (n = x/y) 95%CI

MODS diagnosis of TB

89.0 (332/373) [85.4, 91.9]

92.3 (310/336) [88.9, 94.9]

92.7 (332/358) [89.5, 91.5]

88.3 (310/351) [84.5, 91.5]

MODS for detection of INH resistant isolates

72.6 (45/62) [59.8, 83.1]

97.9 (233/238) [95.2, 99.3]

90.0 (45/50) [78.2, 96.7]

93.2 (233/250) [89.3, 95.9]

MODS for detection of RIF resistant isolates

72.7 (8/11) [39.0, 93.9]

99.7 (288/289) [98.1, 99.9]

88.9 (8/9)

[51.8, 99.7]

98.9 (290/292) [97.5, 99.9]

MODS for detection of MDR isolates

77.8 (7/9)

[39.9, 97.1]

99.7 (290/291) [98.1, 99.6]

87.5 (7/8)

[47.3, 99.6]

99.3 (290/292) [97.5, 99.9]

  1. PPV: Positive predictive value
  2. NPV: Negative predictive value