From: Altered serum microRNAs as biomarkers for the early diagnosis of pulmonary tuberculosis infection
 | Patients group | Healthy controls group | ||
---|---|---|---|---|
 | Low-Density Array study | Validation study | Low-Density Array study | Validation study |
Number of participants | 20 | 30 | 20 | 65 |
Gender (male/female) | 10/10 | 18/12 | 10/10 | 35/30 |
Age (years, mean) | 39.2 ± 16.8 | 44.0 ± 14.2 | 39.5 ± 16.6 | 45.3 ± 20.9 |
Smoking (Yes/no) | 4/20 | 5/30 | 4/20 | 10/65 |
Primary pulmonary lesion by radiography | 10 | 28 | 0 | 0 |
Sputum smear (positive) | 20 | 30 | 0 | 0 |
Culture-positive TB | 20 | 30 | NA | NA |
BCG vaccination (yes/no) | 11/5 | 18/6 | 20/0 | 65/0 |
IGRA-positive TB | 20 | 30 | 0/20 | 0/65 |
HIV | - | - | - | - |