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Table 1 Demographic characteristics of TB patients and healthy controls

From: Altered serum microRNAs as biomarkers for the early diagnosis of pulmonary tuberculosis infection

 

Patients group

Healthy controls group

 

Low-Density Array study

Validation study

Low-Density Array study

Validation study

Number of participants

20

30

20

65

Gender (male/female)

10/10

18/12

10/10

35/30

Age (years, mean)

39.2 ± 16.8

44.0 ± 14.2

39.5 ± 16.6

45.3 ± 20.9

Smoking (Yes/no)

4/20

5/30

4/20

10/65

Primary pulmonary lesion by radiography

10

28

0

0

Sputum smear (positive)

20

30

0

0

Culture-positive TB

20

30

NA

NA

BCG vaccination (yes/no)

11/5

18/6

20/0

65/0

IGRA-positive TB

20

30

0/20

0/65

HIV

-

-

-

-

  1. TB, tuberculosis; BCG, Bacillus Calmette-Guérin vaccine; IGRA, IFN-γ release assay. NA, not applicable; HIV, Human immunodeficiency virus.