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Table 2 Univariate conditional logistic analysis of risk factors for cryptococcal meningitis among patients with meningitis and encephalitis
| Factors | Case [no.(%)] (n = 13) | Control [no.(%)] (n = 52) | P value | OR (95%CI) |
|---|---|---|---|---|
| Gender | ||||
| Female | 9 (21.4) | 51 (55.4) | Reference | |
| Male | 14 (78.6) | 41 (44.6) | 0.190 | 1.81 (0.75-4.38) |
| Age, years | ||||
| 0-5 | 4 (17.4) | 36 (39.1) | Reference | |
| 5-10 | 6 (26.1) | 29 (31.5) | 0.612 | 1.51 (0.31-7.35) |
| 10-15 | 9 (39.1) | 21 (22.8) | 0.033 | 4.36 (1.12-9.81) |
| 15-17 | 4 (17.4) | 6 (6.5) | 0.029 | 5.53 (1.19-25.79) |
| Geographic location | ||||
| Urban areas | 6 (26.1) | 32 (34.8) | Reference | |
| Rural areas | 17 (73.9) | 60 (65.2) | 0.384 | 1.75 (0.54-5.66) |
| Time from illness onset to hospitalization (days) | ||||
| 1-10 | 2 (8.7) | 35 (38.0) | Reference | |
| 10-20 | 3 (13.0) | 24 (26.1) | 0.398 | 2.22 (0.35-14.15) |
| 20-30 | 12 (52.2) | 17 (18.5) | 0.004 | 11.39 (2.20-59.02) |
| ≥30 | 6 (26.1) | 16 (17.4) | 0.055 | 5.05 (0.96-26.84) |
| Contact with birds/droppings or saprophytes* | ||||
| No | 5 (21.7) | 56 (60.9) | Reference | |
| Yes | 18 (78.3) | 36 (39.1) | 0.001 | 9.32 (2.54-34.23) |
| Underlying disease† | ||||
| No | 17 (73.9) | 80 (87.0) | Reference | |
| Yes | 6 (26.1) | 12 (13.0) | 0.160 | 2.05 (0.75-5.58) |
