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Table 3 Independent variables associated with infection by MDR, MDR gram-negatives and pathogens from the ESKAPE group

From: Additional risk factors for infection by multidrug-resistant pathogens in healthcare-associated infection: a large cohort study

Variables MDR, n (%) n = 123 Adjusted OR CI95% p-value MDR Gram negatives, n (%) n = 104 Adjusted OR CI95% p-value ESKAPE pathogens, n(%) n= 41 Adjusted OR CI95% p-value
Age   1.7 1.3-2.3 0.001   1.5 1.1-2.1 0.009     
  ≤60 years 33 (27)     30 (28)     13 (32)    
  61-80 years 44 (36)     37 (36)     13 (32)    
  >80 years 46 (37)     37 (36)     15 (36)    
Previous antibiotic therapy 38 (31)     30 (29)     20 (49) 7.2 3.1-17.0 <0.001
Hospitalization in the previous year (4 months - 1 year) 37 (30) 2.0 1.2-3.4 0.008 29 (28) 1.7 1.0-3.0 0.048 14 (34)    
Karnofsky index<70 57 (46)     44 (42)     22 (54) 3.7 1.6-8.6 0.003
  1. Selection of variables significantly and independently associated with infection by a MDR pathogen, MDR gram negative or a pathogen from the ESKAPE group, among the group of patients admitted from the community (with community or healthcare-associated infection), using multiple logistic regression.
  2. *increase in the odds per category of age; MDR – multi-drug resistant; OR – odds ratio; CI – confidence interval; ESKAPE - Vancomycin-resistant Enterococcus faecium, MRSA, ESBL producing E. coli and Klebsiella species, Klebsiella pneumonia Carbapenamase-hydrolyzing and MDR Acinectobacter baumannii, Pseudomonas aeruginosa and Enterobacter species.