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Table 1 Univariate analysis for clinical characteristics of patients infected or colonized with RPKP and RNKP isolates

From: Epidemic of Klebsiella pneumoniae ST11 Clone Coproducing KPC-2 and 16S rRNA Methylase RmtB in a Chinese University Hospital

Characteristics Patients with RPKP (n = 35) Patients with RNKP (n = 29) P value
Male sex 28(80.0) 21(72.4) 0.79
Age, mean years ± SD 63 ± 13.8 63 ± 18.9 0.988
Ward
ICU 17(48.6) 17(58.6) 0.68
Medicine 6(17.1) 2(6.9) 0.45
Surgery 12(34.3) 10(34.5) >0.99
Transferred from another hospital 15(42.9) 13(44.8) 0.92
Total length of stay in any hospital before isolation of KPC-KP,    
mean days ± SD 18.7 ± 15.1 16.2 ± 15.0 0.525
Total length of stay until discharge or death, mean days ± SD 36.1 ± 22.2 35.6 ± 22.4 0.94
Route of acquisition of KPC-KP    0.203
Imported 4(11.4) 7(24.1) --
Acquired in our hospital 31(88.6) 22(75.9) --
Site of KPC-KP isolation
Bronchial secretion 15(42.9) 12(41.4) >0.99
Blood 6(17.1) 10(34.5) 0.27
Drainage 7(20.0) 6(20.7) >0.99
Urine 4(11.4) 1(3.4) 0.38
Cerebrospinal fluid 2(5.7) 0 --
Pus 1(2.9) 0 --
Infection 31(88.6) 28(96.6) 0.37
Median APACHEII score 17(2–37) 16(2–35) 0.129
Median Charlson score 2(0–10) 2(0–5) 0.233
Invasive procedures
Surgery within a month 16(45.7) 15(51.7) 0.83
Mechanical ventilation 18(51.4) 18(62.1) 0.68
Renal replacement therapy 11(31.4) 9(31.0) >0.99
Drainage catheters 33(94.3) 20(68.9) 0.46
Total times of bed transfer during this hospitalization, mean times ± SD 2.54 ± 1.31 2.52 ± 1.38 0.94
Total times of bed transfer after KPC-KP isolation, mean times ± SD 1.57 ± 0.95 1.66 ± 0.94 0.72
Antibiotic therapy during the last month
Piperacillin-tazobactam 6(17.1) 5(17.2) >0.99
Third-generation cephalosporins 21(60.0) 21(72.4) 0.69
Carbapenems 21(60.0) 13(44.8) 0.53
Quinolones 10(28.6) 3(10.3) 0.22
Fosfomycin 2(5.7) 1(3.4) >0.99
Aminoglycosides 0 1(3.4) --
Minocycline 1(2.9) 0 --
Crude mortality 8(22.9) 8(27.6) 0.77
Attributable mortality 6(19.4)a 5(17.9) 0.88
  1. Footnotes. Data are no. (%) of patients. RPKP, rmtB-positive KPC-producing K. pneumoniae; RNKP, rmtB-negative KPC-producing K. pneumoniae; APACHE II, Acute Physiology and Chronic Health Evaluation II score; ICU, intensive care unit; SD, standard deviation.
  2. a the denominator was the number of patients with infection.