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Table 3 Association between carriage of Streptococcus pneumoniae, nontypeable Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus individually or any of the otopathogens at age 1- < 3 months and subsequent diagnosis of otitis media adjusting for age and sex, presence of other bacteria, and environmental factors

From: Association between early bacterial carriage and otitis media in Aboriginal and non-Aboriginal children in a semi-arid area of Western Australia: a cohort study

Adjusted factors

Aboriginality

Any otopathogena

S. pneumoniae

M. catarrhalis

H. influenzae

S. aureus

 

OR (95%CI)b

OR (95%CI)

OR (95%CI)

OR (95%CI)

OR (95%CI)

Sex and Age only

Aboriginal

3.86 (1.61-9.24)

1.39 (0.64-3.01)

1.97 (0.89-4.39)

5.32 (2.12-13.35)

0.64 (0.26-1.56)

Non-Aboriginal

1.47 (0.80-2.71)

1.12 (0.50-2.47)

2.57 (1.35-4.91)

1.1 (0.36-3.42)

1.02 (0.58-1.77)

Presence of other bacteria

Aboriginal

3.68 (1.51-8.96)

0.86 (0.39-1.93)

1.72 (0.74-3.96)

5.32 (1.95-14.49)

0.6 (0.25-1.47)

Non-Aboriginal

1.48 (0.80-2.72)

0.77 (0.32-1.88)

2.81 (1.40-5.61)

0.96 (0.33-2.83 )

1.06 (0.61-1.86)

Environmental factors c

Aboriginal

2.54 (0.93-6.93)

1.14 (0.49-2.65)

0.81 (0.29-2.27)

3.66 (1.31-10.25)

0.54 (0.22-1.33)

Non-Aboriginal

1.41 (0.78-2.55)

1.07 (0.51-2.28)

2.42 (1.31-4.48)

0.87 (0.32-2.39)

1.06 (0.58-1.93)

All confounders

Aboriginal

2.44 (0.88-6.78)

0.84 (0.32-2.17)

1.02 (0.34-3.10)

3.71 (1.22-11.23)

0.52 (0.20-1.33)

Non-Aboriginal

1.42 (0.78-2.56)

0.81 (0.33-2.00)

2.63 (1.32-5.23)

0.80 (0.30-2.09)

1.05 (0.58-1.91)

  1. All associations adjusted for sex, age and age2.
  2. a Any otopathogen includes one or more of S. pneumoniae, nontypeable Haemophilus influenzae and Moraxella catarrhalis.
  3. b Odds ratio and 95% confidence interval comparing the odds of diagnosis of OM between those who carried the respective organisms at age 1- < 3 months and those who did not.
  4. c Environmental factors are: passive smoking, crowding, other children living in the house and also exclusive breast-feeding at 6–8 weeks.