|
Variable
|
Standard Strategy
|
QFT-GIT Strategy
|
Incremental
|
|---|
|
Costs
| | | |
|
Costs per Individual
| | | |
|
QFT-GIT testing costs
|
$0.00
|
$43.51
|
$43.51
|
|
LTBI treatment and monitoring
|
$275.39
|
$208.99
|
-$66.40
|
|
Total LTBI-care costs
|
$275.39
|
$252.50
|
-$22.89
|
|
Active TB costs per individual*
|
$84.54
|
$117.54
|
$33.00
|
|
Net costs per individual
|
$359.93
|
$370.04
|
$10.12
|
|
Effects
| | | |
|
QALYs**
|
25.21 per referral
|
25.22 per referral
|
0.01 QALYs gained per referral
|
|
Active TB
|
9.9 per 1000 referrals
|
13.7 per 1000 referrals
|
3.8 per 1000 referrals
|
|
Cost-Effectiveness
| | | |
|
Base-Case
|
--
|
--
|
$1,202 per QALY-gained†
|
-
Note. QFT-GIT = QuantiFERON-TB Gold In-Tube; LTBI = latent tuberculosis infection; TB = tuberculosis; BCHD = Baltimore City Health Department; QALYs = Quality-Adjusted Life Years.
- *Active TB costs attributable to individuals referred to the BCHD TB Control Program who go on to develop active TB disease later in life; future costs were discounted at 3%.
- **Future QALY’s were discounted at 3%.
- †ICER calculated as incremental costs divided by incremental effects ($10.12/0.01QALY’s gained).
