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Table 2 Costs and Effects of Intervention Compared to Standard Algorithm in the Base-Case

From: QuantiFERON-TB gold in-tube implementation for latent tuberculosis diagnosis in a public health clinic: a cost-effectiveness analysis

Variable Standard Strategy QFT-GIT Strategy Incremental
Costs    
Costs per Individual    
QFT-GIT testing costs $0.00 $43.51 $43.51
LTBI treatment and monitoring $275.39 $208.99 -$66.40
Total LTBI-care costs $275.39 $252.50 -$22.89
Active TB costs per individual* $84.54 $117.54 $33.00
Net costs per individual $359.93 $370.04 $10.12
Effects    
QALYs** 25.21 per referral 25.22 per referral 0.01 QALYs gained per referral
Active TB 9.9 per 1000 referrals 13.7 per 1000 referrals 3.8 per 1000 referrals
Cost-Effectiveness    
Base-Case -- -- $1,202 per QALY-gained†
  1. Note. QFT-GIT = QuantiFERON-TB Gold In-Tube; LTBI = latent tuberculosis infection; TB = tuberculosis; BCHD = Baltimore City Health Department; QALYs = Quality-Adjusted Life Years.
  2. *Active TB costs attributable to individuals referred to the BCHD TB Control Program who go on to develop active TB disease later in life; future costs were discounted at 3%.
  3. **Future QALY’s were discounted at 3%.
  4. †ICER calculated as incremental costs divided by incremental effects ($10.12/0.01QALY’s gained).