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Table 1 Clinical scoring system for mice infected with Clostridium difficile

From: Adenosine A2A receptor activation reduces recurrence and mortality from Clostridium difficileinfection in mice following vancomycin treatment

Category

Scores*

 

0

1

2

3

Activity

normal

Alert/slow moving

Lethargic/shaky

Inactive unless prodded

Posture

normal

Back slanted

Hunched

Hunched/nose down

Coat

normal

Piloerection

Rough skin

Very ruffled/puff/ Ungroomed

Diarrhea

normal

Soft stool/discolored (yellowish)

Wet stained tail/ mucous +/- blood

Liquid/no stool (ileus)

Eyes/Nose

normal

Squinted ½ closed

Squinted/discharge

Closed/discharge

  1. *Clinical Score=sum of all parameter scores. Total possible score=15. Normal=0; Found dead=15.