|
Characteristic
|
Good outcome
|
Adverse outcome
|
Univariate
|
Multivariate, OR, 95% CI, p-value
|
|---|
| |
GOS > 3, alive
|
GOS≤3/death
|
OR, 95% CI
| |
|---|
|
Age, mean (SD)
|
45 (15.9)
|
52 (15.6)
|
1.03, 1.0-1.06
|
1.02,0.98-1.07, p=0.28
|
|
No predisposing factors
|
48
|
7 (13%)
|
3.5, 1.3-9.4
|
9.3, 1.6-54.7, p=0.014
|
|
Comorbidity
|
31
|
16 (34%)
| | |
|
GCS at presentation
| | | | |
|
12-15
|
68
|
11(14%)
|
1.0
|
1.0
|
|
8-11
|
7
|
3 (30%)
|
1.7, 0.6-12
|
3.5, 0.7-17.5, p=0.113
|
|
<8
|
1
|
8 (89%)
|
26.5, 3.6-381
|
80.6, 2.5-2574, p=0.013
|
|
Burr hole aspiration
|
54 (79%)
|
14 (21%)
|
1.0
| |
|
Craniotomy
|
17 (81%)
|
4 (19%)
|
0.9, 0.3-3.1
| |
|
Medical
|
8 (62%)
|
5 (38%)
|
2.4, 0.7-8.5
| |
|
Duration of symptoms before admission, days median (IQR)
|
4.0 (0–10)
|
3.0 (0–7)
|
0.99, 0.97-1.03
| |
|
Time from admission to surgery, days median (IQR)
|
5.0 (1–13)
|
7.0 (1–14)
|
1.02, 0.97-1.07
| |
|
Intraventricular rupture of brain abscess
|
4 (40%)
|
6 (60%)
|
6.6 ,1.7-26.2
|
11.5, 2.5-53.2, p=0.002
|
|
Meningitis*
|
20 (25%)
|
11 (48%)
|
2.7, 1.03-7.1
|
1.5, 0.3-6.3, p=0.597
|
|
Streptococcus species
|
45 (82%)
|
10 (18%)
| | |
|
Staphylococci
|
9 (60%)
|
6 (40%)
| | |
|
Gram-negative species
|
5 (83%)
|
1 (17%)
| | |
|
Anaerobic bacteria
|
7 (87%)
|
1 (13%)
| | |
|
Other
|
4 (100%)
|
0
| | |
|
Negative culture
|
9 (54%)
|
5 (36%)
| | |
|
Total n
|
79 (77%)
|
23 (23%)
| | |
- GOS: Glasgow Outcome score, GCS: Glasgow Coma Score, IQR: Inter quartile range. Bacterial species were omitted from logistic regression analysis due to limited number in each group and no significant difference in outcome in univariate analysis. *: Defined as positive spinal fluid culture and/or elevated CSF leukocytes (>15 cells/ μl).
