Table 6 Predictors of adverse outcome, logistic regression analysis
Characteristic | Good outcome | Adverse outcome | Univariate | Multivariate, OR, 95% CI, p-value |
|---|---|---|---|---|
GOS > 3, alive | GOS≤3/death | OR, 95% CI | ||
Age, mean (SD) | 45 (15.9) | 52 (15.6) | 1.03, 1.0-1.06 | 1.02,0.98-1.07, p=0.28 |
No predisposing factors | 48 | 7 (13%) | 3.5, 1.3-9.4 | 9.3, 1.6-54.7, p=0.014 |
Comorbidity | 31 | 16 (34%) | ||
GCS at presentation | ||||
12-15 | 68 | 11(14%) | 1.0 | 1.0 |
8-11 | 7 | 3 (30%) | 1.7, 0.6-12 | 3.5, 0.7-17.5, p=0.113 |
<8 | 1 | 8 (89%) | 26.5, 3.6-381 | 80.6, 2.5-2574, p=0.013 |
Burr hole aspiration | 54 (79%) | 14 (21%) | 1.0 | |
Craniotomy | 17 (81%) | 4 (19%) | 0.9, 0.3-3.1 | |
Medical | 8 (62%) | 5 (38%) | 2.4, 0.7-8.5 | |
Duration of symptoms before admission, days median (IQR) | 4.0 (0–10) | 3.0 (0–7) | 0.99, 0.97-1.03 | |
Time from admission to surgery, days median (IQR) | 5.0 (1–13) | 7.0 (1–14) | 1.02, 0.97-1.07 | |
Intraventricular rupture of brain abscess | 4 (40%) | 6 (60%) | 6.6 ,1.7-26.2 | 11.5, 2.5-53.2, p=0.002 |
Meningitis* | 20 (25%) | 11 (48%) | 2.7, 1.03-7.1 | 1.5, 0.3-6.3, p=0.597 |
Streptococcus species | 45 (82%) | 10 (18%) | ||
Staphylococci | 9 (60%) | 6 (40%) | ||
Gram-negative species | 5 (83%) | 1 (17%) | ||
Anaerobic bacteria | 7 (87%) | 1 (13%) | ||
Other | 4 (100%) | 0 | ||
Negative culture | 9 (54%) | 5 (36%) | ||
Total n | 79 (77%) | 23 (23%) |