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Table 7 Comparison of urinary amino acid concentrations between polytrauma patients on day 5 and healthy volunteers

From: Changes in urine composition after trauma facilitate bacterial growth

Amino acids

D5

HV

HV-D5 mean or median differences [CI95%]

(μmol/lL)

Mean ± SD

Mean ± SD

 

Taurine

324 ± 301

944 ± 597

619.36 [87.15; 1151.57]

Aspartic acid

12 ± 15

8 ± 2

-4.45 [-14.94; 6.03]

Threonine a

778 ± 382

105 ± 23

-672.79 [-944.09; -401.49]

Serine a

841 ± 429

242 ± 42

-598.42 [-903.86; -292.97]

Asparagine a

459 ± 240

72 ± 17

-387.51 [-557.85; -217.18]

Glutamic acid

57 ± 49

10 ± 7

-46.82 [-81.78; -11.85]

Glutamine a

864 ± 365

326 ± 76

-538.03 [-803.53; -272.53]

Glycine a

2049 ± 985

879 ± 211

-1170.10 [-1888.18; -452.03]

Alanine a

390 ± 202

240 ± 56

-123.41 [-268.06; 21.25] b

Citrulline

73 ± 57

15 ± 5

-58.67 [-98.89; -18.44]

Valine

79 ± 46

36 ± 9

-43.29 [-76.66; -9.91]

Cystine

225 ± 209

35 ± 9

-189.76 [-337.97; -41.56]

Methionine a

9 ± 8

5 ± 6

-4.23 [-11.74; 3.28]

Isoleucine

22 ± 16

17 ± 4

-5.13 [-17.04; 6.78]

Leucine

52 ± 32

18 ± 3

-34.34 [-57.07; -11.61]

Tyrosine

222 ± 134

76 ± 30

-146.75 [-244.35; -49.16]

Phenylalanine

258 ± 187

55 ± 10

-202.73 [-334.94; -70.51]

Ornithine

99 ± 132

7 ± 2

-93.38 [-173.72; -13.05] b

Histidine

1267 ± 575

543 ± 159

-724.23 [-1151.22; -297.24]

Lysine

1542 ± 1993

104

-1437.41 [-2849.66; -25.15]

Arginine

54 ± 64

11 ± 95

29.48 [-86.49; 145.45]

  1. D5 on day 5, HV healthy volunteers.
  2. aAmino acids known to be particularly important during growth in urine for E. coli (personal data and [11, 17, 18, 24].
  3. bMedians difference and Hodges-Lehmann 95% Confidence Interval.