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Table 6 Comparison of urinary amino acid concentrations between trauma patients on day 1 and healthy volunteers

From: Changes in urine composition after trauma facilitate bacterial growth

Amino acids

D1

HV

HV-D1 mean or median differences [CI95%]

(μmol/L)

Mean ± SD

Mean ± SD

 

Taurine

738 ± 551

944 ± 597

205.98 [-390.38; 802.35]

Aspartic acid

14 ± 23

8 ± 2

-6.43 [-22.53; 9.66]

Threonine a

339 ± 519

105 ± 23

-233.38 [-601.06; 134.31]

Serine a

525 ± 596

242 ± 42

-283.04 [-686.74; 120.66]

Asparagine a

258 ± 329

72 ± 17

-186.31 [-419.08; 46.47]

Glutamic acid

83 ± 133

10 ± 7

-34.29 [-56.20; -12.37] b

Glutamine a

650 ± 608

326 ± 76

-323.98 [-757.79; 109.83]

Glycine a

1991 ± 2396

879 ± 211

-1111.23 [-2813.86; 591.41]

Alanine a

407 ± 273

240 ± 56

-167.22 [-365.07; 30.64]

Citrulline

74 ± 149

15 ± 5

-59.03 [-164.57; 46.51]

Valine

96 ± 69

36 ± 9

-60.71 [-109.93; -11.48]

Cystine

205 ± 337

35 ± 9

-73.56 [-145.20; -1.92] b

Methionine a

15 ± 11

5 ± 6

-10.23 [-19.00; -1.46]

Isoleucine

26 ± 13

17 ± 4

-9.02 [-19.04; 1.00]

Leucine

61 ± 49

18 ± 3

-43.30 [-77.81; -8.79]

Tyrosine

213 ± 167

76 ± 30

-137.20 [-257.38; -17.03]

Phenylalanine

433 ± 360

55 ± 10

-378.06 [-632.89; -123.23]

Ornithine

135 ± 339

7 ± 2

-13.81 [-26.96; -0.67] b

Histidine

1469 ± 1347

543 ± 159

-768.69 [-1447.56; -89.82] b

Lysine

2000 ± 5164

104

-1896.22 [-5550.61; 1758.18]

Arginine

71 ±147

11 ± 95

-85.12 [-238.12; 67.88]

  1. D1 on day 1, HV healthy volunteers.
  2. aAmino acids known to be particularly important during growth in urine for E. coli (personal data and [11, 17, 18, 24].
  3. bMedians difference and Hodges-Lehmann 95% Confidence Interval.