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Table 1 Characteristics of included studies

From: Association between tumor necrosis factor alpha-238G/a polymorphism and tuberculosis susceptibility: a meta-analysis study

Author

Country (ethnicity)

Cases/controls

Diagnosis of cases

Selection of controls

Selvaraj

India (Asian)

210/120

Smear, culture, radiological, clinical response confirmed PTB

Normal healthy spouses and Tuberculosis Research Centre staff, ethnicity and area of residence matched

Fitness

Malawi (African)

181/533

Smear, culture, histology confirmed TB, HIV negative

No history or symptom of TB; not first or second degree relatives of the cases; age, sex and area of residence matched

Vejbaesya

Thailand (Asian)

149/147

Smear, culture, clinical and radiological response confirmed PTB, HIV negative

Unrelated healthy blood bank donors

Ates

Turkey (Caucasian)

128/80

Smear, culture, pathological, radiological , clinical response confirmed PTB,EPTB

No history of TB noted on chest radiography, age and sex matched

Trajkov

Republic of Macedonia (Caucasian)

75/301

Smear/culture confirmed PTB

No family history of TB, nationality and area of residence matched

Merza

Iran (Asian)

117/60

Smear and radiological confirmed PTB

Nurses, doctors and TB staff with no laboratory or clinical sign of diseases development, age, sex and nationality matched

Sharma

India (Asian)

185/155

Smear, culture, histology, radiological , clinical response confirmed PTB,EPTB,HIV negative without chronic illness

Without a family history of TB or any other related disease and a possibility of a latent tuberculosis infection, socioeconomic status and ethnicity matched

Anoosheh

Iran (Asian)

93/103

Smear and culture confirmed PTB

No history of TB

Lin

China (Asian)

46/40

Pathological examination and clinical response confirmed EPTB

NR

  1. *NR=not reported; HIV = human immunodeficiency virus; PTB= pulmonary tuberculosis; TB = tuberculosis; EPTB= extrapulmonary tuberculosis; HWE= Hardy–Weinberg equilibrium.