Symbols | Description of genes | EV71/control | |
---|---|---|---|
 |  | (Fold changes) | |
 |  | 8 h | 20 h |
ACIN1 | Apoptotic chromatin condensation inducer 1 (ACINUS; ACN; fSAP152) | -3.17 | 1.33 |
AIFM1 | Apoptosis-inducing factor 1 (AIF; COXPD6; PDCD8) | 1.03 | -1.33 |
AIFM2 | Apoptosis-inducing factor, mitochondrion-associated, 2 (AMID; PRG3; RP11-367H5.2) | -3.83 | -1.25 |
Akt1 | V-akt murine thymoma viral oncogene homolog 1 (AKT1; PKB; PKB-ALPHA; PRKBA; RAC; RAC-ALPHA) | -9.89 | -1.13 |
Akt2 | V-akt murine thymoma viral oncogene homolog 2 (AKT2, PKBB; PKBBETA; PRKBB; RAC-BETA) | -3.36 | 2.66 |
Akt3 | V-akt murine thymoma viral oncogene homolog 3(AKT3) | -1.06 | 1.58 |
APAF1 | Apoptotic peptidase activating factor 1 (APAF-1; CED4) | -4.10 | 1.09 |
API5 | Apoptosis inhibitor 5 (AAC-11; AAC11) | -5.41 | 1.06 |
Bcl-2 | B-cell lymphoma 2 (BCL-2) | -1.07 | -1.43 |
BIRC2 | Baculoviral IAP repeat-containing 2 | 1.56 | 1.23 |
BIRC3 | Baculoviral IAP repeat-containing 3 (AIP1; API2; CIAP2; HAIP1; HIAP1; MALT2; MIHC; RNF49; c-IAP2) | -1.84 | 3.19 |
Caspase-3 | Apoptosis-related cysteine peptidase 3(Casp3) | 1.91 | 2.38 |
Caspase-4 | Apoptosis-related cysteine peptidase 4(Casp4) | -1.31 | 1.15 |
Caspase-7 | Apoptosis-related cysteine peptidase 7(Casp7) | -2.15 | 2.03 |
Caspase-8 | Apoptosis-related cysteine peptidase 8(Casp8) | 1.87 | 2.17 |
Caspase-9 | Apoptosis-related cysteine peptidase 9(Casp9) | -4.98 | -1.02 |
Caspase-10 | Apoptosis-related cysteine peptidase 10(Casp10) | 1.25 | 2.16 |
Caspase-12 | Apoptosis-related cysteine peptidase 12 (Casp12) | 1.24 | 1.10 |
CD5 | CD5 molecule | -2.41 | 4.77 |
CD70 | CD70 molecule | 1.55 | 4.04 |
CD40L | CD40 ligand | -2.51 | 5.44 |
CD24 | CD24 molecule | 1.53 | 2.98 |
CD27 | CD27 molecule | -2.37 | 1.71 |
c-Fos | c-fos proto-oncogene | 2.34 | 3.23 |
c-Jun | c-Jun proto-oncogene | 1.69 | 5.52 |
CIDEA | Cell death-inducing DFFA-like effector a | -1.32 | -1.58 |
CIDEB | Cell death-inducing DFFA-like effector b | -2.67 | 2.98 |
DAPK1 | Death-associated protein kinase 1 | -2.80 | 1.24 |
DAPK2 | Death-associated protein kinase 2 | -1.81 | 1.32 |
DAPK3 | Death-associated protein kinase 3 (ZIP; ZIPK) | -10.17 | 2.06 |
DFFA | DNA fragmentation factor subunit alpha (DFF-45; DFF1; ICAD) | -2.09 | -1.14 |
E2F1 | Transcription factor E2F1 (RBAP1; RBBP3; RBP3) | -3.99 | -1.17 |
E2F2 | Transcription factor E2F2 | -1.64 | 1.55 |
EGFR | Epidermal growth factor receptor | -4.78 | 1.38 |
ENDOG | Endonuclease G | -11.37 | 1.06 |
ERBB3 | Receptor tyrosine-protein kinase erbB-3 (ErbB-3; HER3; MDA-BF-1; c-erbB-3; p180-ErbB3; p45-sErbB3; p85-sErbB3) | -2.29 | 1.54 |
FADD | Fas-associated protein with death domain (MORT1) | -1.48 | -1.42 |
FasL | Fas ligand (FAS L, CD95L; CD178; TNFSF6) | -1.14 | 7.53 |
Fas | Fas receptor (ALPS1A; APO-1; APT1; CD95; FAS1; FASTM; TNFRSF6) | -1.23 | 3.26 |
IFN-α2 | Interferon alpha-2 | 1.13 | 1.54 |
IFN-β1 | Interferon beta | 5.22 | 1.47 |
IGF1 | Insulin-like growth factor 1 (IGF-I; IGF1A; IGFI) | -1.14 | -1.15 |
IGF1 R | Insulin-like Growth Factor 1 (IGF-1), Receptor (CD221; IGFIR; IGFR; JTK13) | -3.50 | 1.27 |
IKBKB | inhibitor of nuclear factor kappa-B kinase subunit beta (IKK-beta; IKK2; IKKB; NF-κBIKB) | -3.52 | 1.33 |
IKBKG | inhibitor of nuclear factor kappa-B kinase subunit gamma (AMCBX1; FIP3; IKK-gamma; IP1; IP2; IPD2; NEMO) | -5.76 | 1.40 |
IL-10 | Interleukin 10 | 1.10 | 12.15 |
IL-1α | Interleukin-1 alpha | -2.60 | 1.64 |
IL-1β | Interleukin-1 beta | -2.20 | 1.30 |
IL-2 | Interleukin 2 | 1.24 | 12.15 |
IL-4 | Interleukin 4 | -3.72 | 2.39 |
IL-6R | Interleukin 6 receptor (CD126) | -5.80 | 1.92 |
IL-7 | Interleukin 7 | -1.65 | 1.26 |
IRAK1 | Interleukin-1 receptor-associated kinase 1 | -3.70 | 3.39 |
JAK2 | Janus kinase 2 (JTK10; THCYT3) | 1.06 | -1.21 |
MAP3K1 | Mitogen-activated protein kinase kinase kinase 1 (MAPKKK1; MEKK; MEKK 1; MEKK1; SRXY6) | -4.55 | 1.51 |
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5 (ASK1; MAPKKK5; MEKK5) | -2.39 | 1.99 |
MAP2K4 | Mitogen-activated protein kinase kinase 4 (JNKK1; MAPKK4; MEK4) | -1.06 | 2.54 |
MAP2K7 | Mitogen-activated protein kinase kinase 7(MAPKK7; MEK7) | -1.09 | 3.05 |
MAPK1 | Mitogen-activated protein kinase 1 (ERK; ERK2; ERT1; MAPK2; P42MAPK; PRKM1; PRKM2; p38; p40; p41) | -2.21 | 1.00 |
MAPK3 | Mitogen-activated protein kinase 3(ERK1; HS44KDAP; P44ERK1; P44MAPK; PRKM3; p44-ERK1; p44-MAPK) | -2.74 | 1.67 |
MAPK8 | Mitogen-activated protein kinase 8(JNK; JNK1; SAPK1) | 1.73 | 2.53 |
MAPK9 | Mitogen-activated protein kinase 9(JNK2; JNK2A; JNK2B; SAPK) | 1.02 | 2.25 |
MYD88 | Myeloid differentiation primary response gene (88) | -6.09 | 1.82 |
NF-κB1 | Nuclear factor NF-kappa-B p105 subunit(NFKB-p105; NFKB-p50; NFkappaB; p105; p50) | -4.81 | 1.18 |
NF-κB3 | Transcription factor p65 (RELA; NF-κB p65) | -1.35 | 2.63 |
NF-κBIA | Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IKBA; MAD-3; NFKBI) | 1.49 | 2.96 |
NTRK1 | Neurotrophic tyrosine kinase receptor type 1(MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA) | -2.84 | 1.33 |
PDCD1 | Programmed cell death protein 1( CD279; PD-1; hPD-l) | -1.63 | 4.48 |
PDCD4 | Programmed cell death protein 4 | -1.30 | 1.06 |
PDCD 7 | Programmed cell death protein 7 | 1.87 | 1.42 |
PI3K-α | Phosphoinositide-3-kinase, catalytic, alpha polypeptide(PIK3CA; p110-alpha; PI3K) | -1.26 | 1.04 |
PI3K-γ | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (PIK3CG ; PI3K; PI3Kgamma; PIK3) | -1.40 | 5.18 |
PIK3R2 | Phosphatidylinositol 3-kinase regulatory subunit beta(P85B; p85; p85-BETA) | -2.12 | -1.20 |
PPP3R1 | protein phosphatase 2B regulatory subunit 1(CALNB1; CNB; CNB1) | -1.52 | 1.94 |
RIPK1 | Receptor-interacting serine/threonine-protein kinase 1(RIP; RIP1) | -2.44 | 1.24 |
STAT1 | Signal transducers and activators of transcription (CANDF7; ISGF-3; STAT91) | -6.18 | 4.04 |
STAT5A | Signal transducer and activator of transcription 5A | -1.14 | -1.15 |
STAT5B | Signal transducer and activator of transcription 5B | -3.17 | 1.08 |
TGFB1 | Transforming growth factor beta 1(CED; DPD1; LAP; TGFB; TGFbeta) | -2.23 | -1.15 |
TNF-α | Tumor necrosis factors | -1.97 | 2.19 |
TNFRSF10A | Tumor necrosis factor receptor superfamily member 10A (APO2; CD261; DR4; TRAILR-1; TRAILR1) | -2.82 | 2.03 |
TNFRSF10B | Tumor necrosis factor receptor superfamily member 10B (DR5, CD262, TRICK2, TRICKB, TRAILR2, TRICK2A, TRICK2B) | -2.84 | 1.02 |
P53 | Tumor protein 53(LFS1; TP53; TRP53) | -7.60 | 1.32 |
XIAP | X-linked inhibitor of apoptosis protein(API3; BIRC4; IAP-3; ILP1; MIHA; XLP2; hIAP3) | -1.94 | 2.59 |