Figure 3

Hybridization pattern of spinal tuberculosis specimens with the DNA microarray. a. Hybridization pattern of the M. tuberculosis strain identification (white frame) b. RMP resistance with the rpoB 531 (TCG->TTG) mutation, the hybridization signal of probe TCG531TTG (solid rectangle) being higher than corresponding wild-type probe (dashed rectangle) c. RMP resistance test: rpoB 516 (GAC->GTC) mutation, the hybridization signal of probe GAC516GTC (solid rectangle) being higher than corresponding wild-type probe (dashed rectangle) d, e. INH resistance test: katG 315 (AGC->ACC) mutation, the hybridisation signal of probe katG AGC315ACC (solid rectangles) were higher than corresponding wild-type probe (dashed rectangles) e. INH resistance test: inhA-15 C-T mutation, the hybridisation signal of probe inhA 15C→T (solid rectangles) were higher than corresponding wild-type probe (dashed rectangles).